Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17239661 | 0.88 | NR4A1 (0.54) | NR4A1NR4A2NR4A3PKMPARP10 | |
| SCHEMBL5727403 | 0.87 | NR4A1 (0.53) | NR4A1NR4A2NR4A3PKMPARP10 | |
| SCHEMBL24047115 | 0.86 | NR4A2 (0.73) | NR4A1NR4A2NR4A3PKMPARP10 | |
| SCHEMBL1960673 | 0.86 | NR4A1 (0.72) | NR4A1NR4A2NR4A3PARP10MAOB | |
| SCHEMBL5727237 | 0.85 | SRD5A2 (0.65) | NR4A1NR4A2NR4A3PKMPARP10 | |
| SCHEMBL7181547 | 0.85 | LMNA (0.51) | NR4A1NR4A2NR4A3PKMPARP10 | |
| SCHEMBL17239663 | 0.84 | PPARG (0.53) | NR4A1NR4A2NR4A3PKMPARP10 | |
| SCHEMBL6378011 | 0.84 | SRD5A2 (0.63) | NR4A1NR4A2NR4A3PKMPARP10 | |
| SCHEMBL25686462 | 0.84 | NR4A1 (0.55) | NR4A1NR4A2NR4A3PKMPARP10 | |
| SCHEMBL2984321 | 0.84 | MAOB (0.74) | NR4A1NR4A2NR4A3PKMPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020147353-A1 | Novel flavonoids | VERENIGING CHRISTELIJK WETENSCHAPPELIJK ANDERWIJS (NL) | 2002-10-10 | — | — | US | disclosed |
| EP-1214308-A2 | NOVEL FLAVONOIDS | VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021608-A2 | NOVEL FLAVONOIDS | VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) | 2001-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147353-A1 | Novel flavonoids | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, ABCC8 | NR4A1 12/4885NR4A2 108/4885NR4A3 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.