SCHEMBL17239663

SCHEMBL17239663

O=C(Cc1ccc(OCCOCc2ccccc2)cc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.53
MAPT P10636 2/20 0.50
ALDH1A1 P00352 1/20 0.50
GAA P10253 1/20 0.50
HTT P42858 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
ALOX5 P09917 2/20 0.49
STS P08842 1/20 0.49
NR4A1 P22736 1/20 0.49
NR4A2 P43354 1/20 0.49
NR4A3 Q92570 1/20 0.49
PKM P14618 1/20 0.47
MAOB P27338 1/20 0.47
PARP10 Q53GL7 1/20 0.47
HRH2 P25021 1/20 0.46
HRH1 P35367 1/20 0.46
EGFR P00533 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17239661 0.96 NR4A1 (0.54) PPARGMAPTL3MBTL1STSNR4A1
SCHEMBL5727403 0.94 NR4A1 (0.53) MAPTL3MBTL1STSNR4A1NR4A2
SCHEMBL7181547 0.92 LMNA (0.51) MAPTRAB9AL3MBTL1STSNR4A1
SCHEMBL3099537 0.91 L3MBTL1 (0.56) MAPTALDH1A1GAAHTTRAB9A
SCHEMBL5725683 0.91 L3MBTL1 (0.62) PPARGMAPTALDH1A1GAAHTT
SCHEMBL12559110 0.87 MAPT (0.46) PPARGMAPTALDH1A1GAAHTT
SCHEMBL7550951 0.84 NR4A1 (0.54) PPARGMAPTALDH1A1GAAHTT
SCHEMBL5727237 0.84 SRD5A2 (0.65) PPARGMAPTALDH1A1GAAHTT
SCHEMBL6378011 0.82 SRD5A2 (0.63) PPARGMAPTALDH1A1GAAHTT
SCHEMBL24047115 0.82 NR4A2 (0.73) RAB9ASMN1; SMN2NR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150321983-A1 A PROCESS FOR THE PREPARATION OF OSPEMIFENE FERMION OY (FI) 2015-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150321983-A1 A PROCESS FOR THE PREPARATION OF OSPEMIFENE CYP2F1, OGFR, OPRM1 PPARG 2582/4885MAPT 1435/4885ALDH1A1 75/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.