Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.36 |
| ▸ | KDM5A | P29375 | 5/20 | 0.36 |
| ▸ | KDM4A | O75164 | 6/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.34 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558930 | 1.00 | LMNA (0.41) | LMNAALDH1A1BCHEACHEEPHX2 | |
| SCHEMBL7557928 | 1.00 | LMNA (0.41) | LMNAALDH1A1BCHEACHEEPHX2 | |
| SCHEMBL7557868 | 1.00 | LMNA (0.41) | LMNAALDH1A1BCHEACHEEPHX2 | |
| SCHEMBL5209079 | 0.91 | LMNA (0.44) | LMNAALDH1A1BCHEACHEEPHX2 | |
| SCHEMBL11782469 | 0.89 | LMNA (0.50) | LMNAALDH1A1BCHEACHEEPHX2 | |
| SCHEMBL7553236 | 0.84 | EPHX2 (0.47) | ALDH1A1BCHEACHEEPHX2KDM4C | |
| SCHEMBL7558693 | 0.84 | EPHX2 (0.47) | ALDH1A1BCHEACHEEPHX2KDM4C | |
| SCHEMBL7552637 | 0.84 | EPHX2 (0.47) | ALDH1A1BCHEACHEEPHX2KDM4C | |
| SCHEMBL7555480 | 0.84 | EPHX2 (0.47) | ALDH1A1BCHEACHEEPHX2KDM4C | |
| SCHEMBL2058434 | 0.83 | ALDH1A1 (0.54) | ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |