Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709015 | 0.87 | PDE4B (0.36) | PDE4BMEN1KMT2APTPN1RIPK1 | |
| SCHEMBL8707829 | 0.73 | PDE4B (0.43) | PDE4BMEN1KMT2APTPN1 | |
| SCHEMBL30307535 | 0.73 | TSHR (0.44) | PDE4B | |
| SCHEMBL6784478 | 0.73 | TSHR (0.44) | PDE4B | |
| SCHEMBL19389725 | 0.72 | PTPN1 (0.34) | PDE4BPTPN1 | |
| SCHEMBL18156614 | 0.70 | PDE4B (0.34) | PDE4BPTPN1 | |
| SCHEMBL18156613 | 0.70 | DHFR (0.38) | MEN1KMT2A | |
| SCHEMBL8398144 | 0.70 | IDO1 (0.31) | MEN1KMT2A | |
| SCHEMBL18176752 | 0.69 | HPGD (0.36) | PDE4BMEN1KMT2APTPN1ALDH1A1 | |
| SCHEMBL29232338 | 0.68 | HSD11B1 (0.40) | MEN1KMT2AALDH1A1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999045008-A1 | 3-[4-(4-CYANOPHENYL)THIAZOL-2-Y)]-1-(1H-1,2,4-TRIAZOL-1-YL)-BUTAN-2-OL DERIVATIVES HAVING ANTIFUNGAL ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-10 | — | — | WO | claimed |