SCHEMBL7551114

SCHEMBL7551114

CC(C)CC(NC(=O)CNC(=O)C(CC(C)C)NC(=O)C1CCCN1C(=O)OC(C)(C)C)C(=O)NC(CC(N)=O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.58
NMUR2 Q9GZQ4 10/20 0.45
NMUR1 Q9HB89 10/20 0.45
POLB P06746 1/20 0.44
NAA50 Q9GZZ1 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
NTSR1 P30989 3/20 0.41
NTSR2 O95665 1/20 0.41
REN P00797 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7146326 1.00 KMT2A (0.58) KMT2ANMUR2NMUR1POLBNAA50
SCHEMBL7550451 0.92 KMT2A (0.68) KMT2APOLBSMN1; SMN2
SCHEMBL7152157 0.92 KMT2A (0.68) KMT2APOLBSMN1; SMN2
SCHEMBL29508500 0.87 KMT2A (0.56) KMT2APOLBSMN1; SMN2
SCHEMBL10781896 0.84 KMT2A (0.58) KMT2APOLBSMN1; SMN2
SCHEMBL10788724 0.84 KMT2A (0.65) KMT2APOLBSMN1; SMN2
SCHEMBL10788732 0.84 KMT2A (0.65) KMT2APOLBSMN1; SMN2
SCHEMBL30487448 0.84 KMT2A (0.73) KMT2APOLBSMN1; SMN2
SCHEMBL30689138 0.83 KMT2A (0.54) KMT2APOLBSMN1; SMN2
SCHEMBL10794138 0.82 KMT2A (0.62) KMT2APOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020173452-A1 Cytostatic-glycoconjugates having specifically cleavable linking units BAYER AKTIENGESELLSCHAFT (DE) 2002-11-21 US disclosed
EP-1219634-A1 Cytostatic-glycoconjugates having specifically cleavable peptidic linking units Bayer Aktiengesellschaft (DE) 2002-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020173452-A1 Cytostatic-glycoconjugates having specifically cleavable linking units CTSE, CTSL, CTSZ KMT2A 3269/4885NMUR2 1827/4885NMUR1 1379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.