SCHEMBL755188

SCHEMBL755188

COCCOC(=O)CC#N

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
ADORA2A P29274 1/20 0.37
MCL1 Q07820 4/20 0.37
DGKA P23743 1/20 0.33
ADRA2A P08913 1/20 0.31
ADRA1A P35348 1/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 3/20 0.30
MAPT P10636 2/20 0.30
BLM P54132 1/20 0.30
KDM4E B2RXH2 2/20 0.30
HSD17B10 Q99714 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2013766 0.94 TSHR (0.35) TSHRADORA2AMCL1DGKAALDH1A1
SCHEMBL11287855 0.94 TSHR (0.35) TSHRADORA2AMCL1DGKAALDH1A1
SCHEMBL6890414 0.89 MCL1 (0.43) MCL1DGKAADRA2AADRA1AMAPT
SCHEMBL28913810 0.88 ALDH1A1 (0.41) TSHRMCL1DGKAALDH1A1
SCHEMBL667293 0.88 ALDH1A1 (0.36) TSHRMCL1DGKAALDH1A1MEN1
SCHEMBL31235634 0.83 ALDH1A1 (0.33) TSHRMCL1ALDH1A1MEN1KMT2A
SCHEMBL31235624 0.83 ALDH1A1 (0.33) TSHRMCL1ALDH1A1MEN1KMT2A
SCHEMBL10901343 0.83 ALDH1A1 (0.45) TSHRMCL1DGKAGAAALDH1A1
SCHEMBL29516300 0.82 KDM4E (0.31) TSHRMAPTKDM4EHSD17B10
SCHEMBL28913777 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12187923-B2 Michael-addition-hardening synthetic resin for chemical fixing technology FISCHERWERKE GMBH & CO. KG (DE) 2025-01-07 US claimed
US-12180394-B2 Michael-addition-hardening hybrid system for chemical fixing technology FISCHERWERKE GMBH & CO. KG (DE) 2024-12-31 US claimed
CN-117929615-B Qualitative and quantitative analysis method for impurities in cyanoacrylate adhesive 潍坊德高新材料有限公司 2024-06-28 CN claimed
US-12006457-B2 Graphene quantum dot composite with dielectric matrix, electroluminescent device having the same, and method for manufacturing the graphene quantum dot composite KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2024-06-11 US claimed
CN-116217433-A Preparation method of cyanoacrylate monomer 潍坊德高新材料有限公司 2023-06-06 CN claimed
US-20230002653-A1 MICHAEL-ADDITION-HARDENING HYBRID SYSTEM FOR CHEMICAL FIXING TECHNOLOGY FISCHERWERKE GMBH & CO. KG (DE) 2023-01-05 US claimed
EP-4069792-A1 MICHAEL REACTION-CURING HYBRID SYSTEM FOR USE IN CHEMICAL FASTENING TECHNOLOGY fischerwerke GmbH & Co. KG (DE) 2022-10-12 EP claimed
EP-4069797-A1 MICHAEL REACTION-CURING SYNTHETIC RESIN FOR USE IN CHEMICAL FASTENING TECHNOLOGY fischerwerke GmbH & Co. KG (DE) 2022-10-12 EP claimed
CN-114729253-A Michael addition hardening synthetic resin for chemical fixing technology 费希尔厂有限责任两合公司 2022-07-08 CN claimed
CN-114729224-A Michael addition hardening hybrid system for chemical fixation technology 费希尔厂有限责任两合公司 2022-07-08 CN claimed
US-20210403804-A1 GRAPHENE QUANTUM DOT COMPOSITE WITH DIELECTRIC MATRIX, ELECTROLUMINESCENT DEVICE HAVING THE SAME, AND METHOD FOR MANUFACTURING THE GRAPHENE QUANTUM DOT COMPOSITE KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2021-12-30 US claimed
WO-2021110621-A1 MICHAEL REACTION-CURING HYBRID SYSTEM FOR USE IN CHEMICAL FASTENING TECHNOLOGY FISCHERWERKE GMBH & CO. KG (DE) 2021-06-10 WO claimed
WO-2021110622-A1 MICHAEL REACTION-CURING SYNTHETIC RESIN FOR USE IN CHEMICAL FASTENING TECHNOLOGY FISCHERWERKE GMBH & CO. KG (DE) 2021-06-10 WO claimed
WO-2020130325-A1 GRAPHENE QUANTUM DOT COMPOSITE COMPRISING DIELECTRIC MATRIX, ELECTROLUMINESCENT DEVICE COMPRISING SAME, AND METHOD FOR PREPARING GRAPHENE QUANTUM DOT COMPOSITE 한국과학기술원 2020-06-25 WO claimed
WO-2020002137-A1 CATALYST BASED ON A BETA-OXYGEN ESTER AND USE THEREOF IN A HYDROTREATING AND/OR HYDROCRACKING PROCESS IFP Energies Nouvelles (FR) 2020-01-02 WO claimed
WO-2013028574-A2 AQUEOUS LITHIUM AIR BATTERIES POLYPLUS BATTERY COMPANY (US) 2013-02-28 WO claimed
US-20260146021-A1 PROCESS OF PREPARATION OF METHYLENE DICARBOXYLATES CRACKLESS MONOMERS CO., LTD (TW) 2026-05-28 US disclosed
EP-4748824-A1 PROCESS OF PREPARATION OF METHYLENE DICARBOXYLATES Crackless Monomers Co., Ltd (TW) 2026-05-27 EP disclosed
US-3966767-A CORONARY ACTION, ANTI-HYPERTENSIVE AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed
US-3959306-A Azolindolines and azolindoline dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146021-A1 PROCESS OF PREPARATION OF METHYLENE DICARBOXYLATES FTO, PHOSPHO1, AFF1 TSHR 1063/4885ADORA2A 2644/4885MCL1 799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.