Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287855 | 1.00 | TSHR (0.35) | TSHRADORA2AMCL1ABCB11CYP3A4 | |
| SCHEMBL755188 | 0.94 | TSHR (0.38) | TSHRADORA2AMCL1ALDH1A1HSD17B10 | |
| SCHEMBL3785372 | 0.90 | MCL1 (0.39) | TSHRMCL1ALDH1A1TP53HIF1A | |
| SCHEMBL13557224 | 0.90 | MCL1 (0.39) | TSHRMCL1ALDH1A1TP53HIF1A | |
| SCHEMBL31235624 | 0.85 | ALDH1A1 (0.33) | TSHRMCL1ALDH1A1 | |
| SCHEMBL31235634 | 0.85 | ALDH1A1 (0.33) | TSHRMCL1ALDH1A1 | |
| SCHEMBL3783247 | 0.85 | ALDH1A1 (0.50) | TSHRMCL1ALDH1A1TP53HIF1A | |
| SCHEMBL28716408 | 0.85 | ALDH1A1 (0.50) | TSHRMCL1ALDH1A1TP53HIF1A | |
| SCHEMBL10901082 | 0.85 | DGKA (0.38) | TSHRMCL1ALDH1A1TP53HIF1A | |
| SCHEMBL6890414 | 0.83 | MCL1 (0.43) | MCL1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024203772-A1 | METHOD FOR PRODUCING ALPHA-CYANOACRYLATE | 東亞合成株式会社 | 2024-10-03 | — | — | WO | disclosed |
| CN-114269716-A | 2-cyanoacrylate compound and adhesive composition | 东亚合成株式会社 | 2022-04-01 | — | — | CN | disclosed |
| US-10029982-B2 | Light absorptive compound, polymer composition containing the compound, polymer film, and cured layer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-07-24 | — | — | US | disclosed |
| US-20170315137-A1 | AMYLOID BINDING AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-11-02 | — | — | US | disclosed |
| US-20170315137-A1 | AMYLOID BINDING AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-11-02 | — | — | US | disclosed |
| US-20170183304-A1 | LIGHT ABSORPTIVE COMPOUND, POLYMER COMPOSITION CONTAINING THE COMPOUND, POLYMER FILM, AND CURED LAYER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-06-29 | — | — | US | disclosed |
| US-9551722-B2 | Amyloid binding agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-24 | — | — | US | disclosed |
| US-9551722-B2 | Amyloid binding agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-24 | — | — | US | disclosed |
| US-20150177262-A1 | AMYLOID BINDING AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-06-25 | — | — | US | disclosed |
| US-20150177262-A1 | AMYLOID BINDING AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-06-25 | — | — | US | disclosed |
| EP-2509940-B1 | AMYLOID BINDING AGENTS | UNIV CALIFORNIA (US) | 2015-06-10 | — | — | EP | disclosed |
| US-8940918-B2 | Amyloid binding agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940918-B2 | Amyloid binding agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-01-27 | — | — | US | disclosed |
| US-20120302603-A1 | AMYLOID BINDING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-29 | — | — | US | disclosed |
| EP-2509940-A2 | AMYLOID BINDING AGENTS | The Regents of the University of California (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011072257-A2 | AMYLOID BINDING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302603-A1 | AMYLOID BINDING AGENTS | APP, APBA1, PSEN1 | TSHR 4647/4885ADORA2A 2185/4885MCL1 3176/4885 |
| US-20170315137-A1 | AMYLOID BINDING AGENTS | APBA1, APP, PSEN1 | TSHR 4666/4885ADORA2A 2641/4885MCL1 3629/4885 |
| US-20170183304-A1 | LIGHT ABSORPTIVE COMPOUND, POLYMER COMPOSITION CONTAINING THE COMPOUND, POLYMER FILM, AND CURED LAYER | MLN, MLEC, VIP | TSHR 4449/4885ADORA2A 3424/4885MCL1 3801/4885 |
| US-10029982-B2 | Light absorptive compound, polymer composition containing the compound, polymer film, and cured layer | MLN, MLEC, VIP | TSHR 4449/4885ADORA2A 3424/4885MCL1 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.