Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dyrene SCHEMBL504140 | 0.86 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| Dyrene SCHEMBL7191646 | 0.83 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| Dyrene SCHEMBL5483770 | 0.83 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| Dyrene SCHEMBL1029356 | 0.82 | MAPT (0.65) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| Dyrene SCHEMBL4937195 | 0.82 | TSHR (0.48) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| Dyrene SCHEMBL1029941 | 0.79 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| Dyrene SCHEMBL8178116 | 0.74 | TSHR (0.75) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| Dyrene SCHEMBL16113661 | 0.71 | TSHR (0.80) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL984264 | 0.71 | ALDH1A1 (0.44) | MAPTALDH1A1KMT2ATSHRGAA | |
| SCHEMBL982025 | 0.70 | ALDH1A1 (0.42) | MAPTALDH1A1KMT2ATSHRCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002043656-A2 | WATER-IN-OIL INSECT REPELLENT COMPOSITION AND METHOD OF APPLICATION TO THE SKIN | AVON PRODUCTS, INC. (US) | 2002-06-06 | — | — | WO | claimed |