Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dyrene SCHEMBL5954767 | 0.90 | TSHR (0.86) | TSHRMAPTSMN1; SMN2KDM4EALDH1A1 | |
| Dyrene SCHEMBL1029356 | 0.90 | MAPT (0.65) | TSHRMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29609022 | 0.89 | MAPT (0.93) | TSHRMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6237782 | 0.89 | MAPT (0.93) | TSHRMAPTSMN1; SMN2KDM4EALDH1A1 | |
| Dyrene SCHEMBL690206 | 0.88 | TSHR (0.96) | TSHRMAPTSMN1; SMN2KDM4EALDH1A1 | |
| Dyrene SCHEMBL29364667 | 0.87 | TSHR (1.00) | TSHRMAPTSMN1; SMN2KDM4EALDH1A1 | |
| Dyrene SCHEMBL1903290 | 0.87 | TSHR (1.00) | TSHRMAPTSMN1; SMN2KDM4EALDH1A1 | |
| Dyrene SCHEMBL6750152 | 0.87 | TSHR (1.00) | TSHRMAPTSMN1; SMN2KDM4EALDH1A1 | |
| Dyrene SCHEMBL8166670 | 0.87 | TSHR (1.00) | TSHRMAPTSMN1; SMN2KDM4EALDH1A1 | |
| Dyrene SCHEMBL13280 | 0.87 | TSHR (1.00) | TSHRMAPTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000014076-A1 | PROCESS FOR MAKING 2,4-DIHYDROXYPHENYL AND 2-HYDROXY-4-ALKOXYPHENYL SUBSTITUTED TRIAZINE COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-16 | — | — | WO | disclosed |