Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7561008 | 0.99 | MEN1 (0.36) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL7552149 | 0.78 | NOS3 (0.56) | — | |
| SCHEMBL7482734 | 0.78 | NPC1 (0.48) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7561015 | 0.77 | NOS3 (0.55) | — | |
| Hydrochloric Acid SCHEMBL7483114 | 0.77 | NPC1 (0.47) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7555455 | 0.77 | NPC1 (0.47) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL7552141 | 0.76 | F2 (0.33) | ALDH1A1SMN1; SMN2F2PLGPLAU | |
| SCHEMBL7510203 | 0.74 | NPC1 (0.42) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL7506573 | 0.73 | PNMT (0.46) | RAB9ANPC1MAPTLMNANFKB1 | |
| Hydrochloric Acid SCHEMBL7506643 | 0.72 | PNMT (0.45) | RAB9ANPC1MAPTLMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861250-B1 | AMIDINE AND ISOTHIOUREA DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | claimed |