Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482739 | 0.80 | CYP1A2 (0.32) | F2PLGPLAUPLATKLKB1 | |
| SCHEMBL7512695 | 0.76 | F2 (0.31) | F2PLGPLAUPLATKLKB1 | |
| Hydrochloric Acid SCHEMBL7561008 | 0.75 | MEN1 (0.36) | F2PLGPLAUPLATKLKB1 | |
| SCHEMBL7506577 | 0.74 | PNMT (0.44) | — | |
| SCHEMBL7549924 | 0.71 | NPC1 (0.32) | F2PLGPLAUPLATKLKB1 | |
| SCHEMBL7489818 | 0.71 | SMN1; SMN2 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7511439 | 0.70 | PNMT (0.37) | — | |
| SCHEMBL7516507 | 0.70 | PNMT (0.42) | — | |
| SCHEMBL8307723 | 0.70 | DRD2 (0.32) | — | |
| SCHEMBL7512428 | 0.69 | L3MBTL3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861250-B1 | AMIDINE AND ISOTHIOUREA DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | claimed |