Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754468 | 0.84 | MAPT (0.47) | KDM4EMAPTGAAHTT | |
| SCHEMBL30819290 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1HPGDCSNK2A1CSNK2A2 | |
| SCHEMBL15491101 | 0.77 | CSNK2A1 (0.50) | KDM4EALDH1A1HPGDCSNK2A1CSNK2A2 | |
| SCHEMBL16921631 | 0.75 | NOTUM (0.38) | KDM4EALDH1A1HPGDNOTUMMAPT | |
| SCHEMBL2933319 | 0.74 | CSNK2A1 (0.45) | KDM4EALDH1A1HPGDCSNK2A1CSNK2A2 | |
| SCHEMBL1146532 | 0.74 | CSNK2A1 (0.45) | KDM4EALDH1A1HPGDCSNK2A1CSNK2A2 | |
| SCHEMBL2656486 | 0.74 | CSNK2A1 (0.45) | KDM4EALDH1A1HPGDCSNK2A1CSNK2A2 | |
| SCHEMBL13698067 | 0.72 | HSD17B10 (0.42) | KDM4EALDH1A1HPGDNOTUMHSD17B10 | |
| SCHEMBL4742034 | 0.72 | CA2 (0.38) | HSD17B10 | |
| SCHEMBL5153802 | 0.72 | PKM (0.44) | KDM4EALDH1A1HPGDNOTUMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388543-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-12-25 | — | — | US | disclosed |
| EP-2266958-B1 | Antiviral agent | SHIONOGI & CO (JP) | 2017-03-15 | — | — | EP | disclosed |
| EP-3042894-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2016-07-13 | — | — | EP | disclosed |
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |
| EP-2181985-B1 | Antiviral Agent | SHIONOGI & CO (JP) | 2011-10-26 | — | — | EP | disclosed |
| EP-2266958-A1 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2010-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388543-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | SCN8A, SCN1B, SCN3A | KDM4E 4442/4885ALDH1A1 2279/4885HPGD 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.