Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 5/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 5/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 5/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.36 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13698067 | 0.80 | HSD17B10 (0.42) | PKMHSD17B10TDP1MAPTKDM4E | |
| Butane SCHEMBL4112579 | 0.74 | HSD17B10 (0.38) | PKMHSD17B10TDP1MAPTKDM4E | |
| SCHEMBL755293 | 0.72 | KDM4E (0.48) | HSD17B10TDP1MAPTKDM4EALDH1A1 | |
| SCHEMBL5515030 | 0.71 | KDM4E (0.35) | PKMHSD17B10TDP1MAPTKDM4E | |
| SCHEMBL5154326 | 0.69 | KEAP1 (0.40) | TDP1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL30819290 | 0.69 | KDM4E (0.46) | HSD17B10TDP1MAPTKDM4EALDH1A1 | |
| SCHEMBL1505827 | 0.69 | TDP1 (0.61) | PKMHSD17B10TDP1MAPTKDM4E | |
| SCHEMBL6206909 | 0.68 | KDM4E (0.41) | HSD17B10TDP1MAPTKDM4EALDH1A1 | |
| SCHEMBL5173407 | 0.68 | CA12 (0.48) | PKMHSD17B10TDP1MAPTKDM4E | |
| SCHEMBL17417754 | 0.67 | HSD17B10 (0.43) | HSD17B10TDP1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | claimed |
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| EP-1737417-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2007-01-03 | — | — | EP | disclosed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | disclosed |
| WO-2005074875-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, CYB5R3 | PKM 517/4885HSD17B10 588/4885TDP1 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.