Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112949 | 0.96 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL27838730 | 0.82 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL4988971 | 0.82 | SMN1; SMN2 (0.61) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL70297 | 0.82 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL29627490 | 0.82 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL6849222 | 0.82 | MEN1 (0.71) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL13402273 | 0.79 | L3MBTL1 (0.58) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL13596619 | 0.79 | SMN1; SMN2 (0.58) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL31676628 | 0.79 | SMN1; SMN2 (0.58) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL70296 | 0.79 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263472-A2 | MODIFICATION OF BIOPOLYMERS FOR IMPROVED DRUG DELIVERY | GENZYME CORPORATION (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001060412-A2 | MODIFICATION OF BIOPOLYMERS FOR IMPROVED DRUG DELIVERY | GENZYME CORPORATION (US) | 2001-08-23 | — | — | WO | disclosed |