Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.64 |
| ▸ | CTSL | P07711 | 12/20 | 0.64 |
| ▸ | CTSS | P25774 | 11/20 | 0.64 |
| ▸ | CTSB | P07858 | 7/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183072 | 0.89 | CTSK (0.80) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6183542 | 0.81 | CTSL (0.81) | CTSKCTSLCTSSCTSB | |
| SCHEMBL27483446 | 0.81 | CTSK (0.60) | CTSKCTSLCTSSCTSB | |
| SCHEMBL27563904 | 0.81 | CTSK (0.56) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7159540 | 0.81 | CTSK (0.56) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580230 | 0.81 | CTSK (0.60) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7046888 | 0.81 | CTSK (0.56) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7554406 | 0.80 | CTSB (0.61) | CTSKCTSLCTSSCTSB | |
| SCHEMBL27509566 | 0.80 | CTSK (0.55) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7166484 | 0.80 | CTSK (0.55) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161415-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055126-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |