SCHEMBL755369

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22845583	1.00	ALDH1A1 (0.48)	ALDH1A1RECQLTAAR1THRBMMP8
	SCHEMBL22845598	0.85	ALDH1A1 (0.42)	ALDH1A1RECQLTAAR1THRBMMP8
	SCHEMBL21239969	0.82	SLC13A5 (0.62)	ALDH1A1SLC13A5
	SCHEMBL21239968	0.82	SLC13A5 (0.62)	ALDH1A1SLC13A5
	SCHEMBL14510426	0.80	ALDH1A1 (0.42)	ALDH1A1RECQLTAAR1THRBMMP8
	SCHEMBL18065668	0.79	ALDH1A1 (0.51)	ALDH1A1RECQLTAAR1THRBMMP8
	SCHEMBL25907506	0.78	ALDH1A1 (0.47)	ALDH1A1MMP8POLBSLC13A5MAPT
	SCHEMBL15419571	0.77	MMP8 (0.54)	ALDH1A1RECQLTAAR1THRBMMP8
	SCHEMBL7617566	0.77	MMP8 (0.61)	ALDH1A1RECQLTAAR1THRBMMP8
	SCHEMBL30513307	0.77	ALDH1A1 (0.60)	ALDH1A1RECQLTAAR1THRBMMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.