Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560143 | 0.96 | HPGD (0.62) | HPGDRAB9ASMN1; SMN2NPC1CYP2D6 | |
| SCHEMBL7552344 | 0.81 | FFAR1 (0.55) | FFAR1 | |
| SCHEMBL25175801 | 0.79 | CYP2D6 (0.50) | HPGDRAB9ASMN1; SMN2NPC1CYP2D6 | |
| SCHEMBL8093089 | 0.78 | HDAC1 (0.58) | HPGDRAB9ASMN1; SMN2NPC1CYP2D6 | |
| SCHEMBL7556540 | 0.77 | FFAR1 (0.56) | HPGDFFAR1 | |
| SCHEMBL7552622 | 0.77 | CYP2D6 (0.58) | CYP2D6 | |
| SCHEMBL7557375 | 0.77 | CNR1 (0.55) | HPGDSMN1; SMN2CYP2D6KMT2A | |
| SCHEMBL22813680 | 0.75 | SIGMAR1 (0.62) | HPGDSMN1; SMN2NPC1ALDH1A1TDP1 | |
| SCHEMBL3022692 | 0.74 | CYP2D6 (0.94) | CYP2D6CACNA1B | |
| SCHEMBL3637520 | 0.73 | CYP2D6 (0.92) | CYP2D6CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |