SCHEMBL755376

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL755375	1.00	MAPT (0.41)	MAPTMEN1KMT2ALMNANPSR1
	SCHEMBL13754949	0.90	MEN1 (0.40)	MEN1KMT2ALMNAALDH1A1PTPN1
	SCHEMBL13754983	0.82	ALDH1A1 (0.40)	MEN1KMT2AALDH1A1PTPN1KDM4E
	SCHEMBL753117	0.81	MAPT (0.42)	MAPTMEN1KMT2ALMNANPSR1
	SCHEMBL18590767	0.81	LMNA (0.42)	MAPTMEN1KMT2ALMNANPSR1
	SCHEMBL753116	0.81	MAPT (0.42)	MAPTMEN1KMT2ALMNANPSR1
	SCHEMBL757267	0.76	NR3C2 (0.44)	MAPTMEN1KMT2ALMNANPSR1
	SCHEMBL757266	0.76	NR3C2 (0.44)	MAPTMEN1KMT2ALMNANPSR1
	SCHEMBL753244	0.73	MAPT (0.46)	MAPTMEN1KMT2ALMNANPSR1
	SCHEMBL753245	0.73	MAPT (0.46)	MAPTMEN1KMT2ALMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.