SCHEMBL7555076

SCHEMBL7555076

Nc1cc(NC(=O)c2ccccc2)ccc1S(=O)(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 2/20 0.54
KCNK9 Q9NPC2 2/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA9 Q16790 1/20 0.54
PRMT1 Q99873 2/20 0.54
ACE2 Q9BYF1 1/20 0.52
NPC1 O15118 6/20 0.51
RAB9A P51151 6/20 0.51
KMT2A Q03164 6/20 0.50
MEN1 O00255 4/20 0.50
PLAU P00749 1/20 0.50
PTPN1 P18031 1/20 0.50
HPGD P15428 1/20 0.50
JAK2 O60674 1/20 0.49
JAK1 P23458 1/20 0.49
SIRT1 Q96EB6 2/20 0.49
PKM P14618 1/20 0.49
TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4905389 0.88 MEN1 (0.60) CA12CA1CA2CA9PRMT1
SCHEMBL8673667 0.88 KCNK3 (0.54) KCNK3KCNK9CA12CA1CA2
SCHEMBL4903434 0.87 PTGS1 (0.54) PRMT1KMT2AMEN1SIRT1TP53
SCHEMBL10797547 0.86 MAOA (0.56) NPC1RAB9AKMT2AMEN1PKM
SCHEMBL10803115 0.86 KCNK3 (0.58) KCNK3KCNK9NPC1RAB9AKMT2A
SCHEMBL11706364 0.86 PRMT1 (0.56) KCNK3PRMT1NPC1RAB9AKMT2A
SCHEMBL10800759 0.86 NPC1 (0.57) NPC1RAB9AKMT2AMEN1HPGD
SCHEMBL10785305 0.85 HDAC2 (0.54) PRMT1NPC1RAB9AKMT2AMEN1
SCHEMBL10802519 0.85 CYP1A2 (0.55) CA12CA9KMT2AMEN1MAPT
SCHEMBL8901241 0.84 FADS1 (0.56) CA12CA1CA2CA9NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1090656-C Monoazo pigments AVECIA LTD (GB) 2002-09-11 CN claimed
EP-0804509-B1 MONOAZO PIGMENTS AVECIA LTD (GB) 2002-07-24 EP disclosed
US-5919915-A Azo pyrazolone pigments ZENECA LIMITED (GB) 1999-07-06 US disclosed
EP-0804509-A1 MONOAZO PIGMENTS ZENECA LIMITED (GB) 1997-11-05 EP disclosed
WO-1996022333-A1 MONOAZO PIGMENTS ZENECA LIMITED (GB) 1996-07-25 WO disclosed
US-4937326-A Colorfastness SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-06-26 US disclosed
US-4703112-A COLOR FASTNESS, ACID RESISTANCE HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-27 US disclosed
EP-0052985-B1 REACTIVE MONOAZO SCARLET DYES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-09-05 EP disclosed
EP-0052985-A1 Reactive monoazo scarlet dyes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-02 EP disclosed
US-4283331-A FIBER-REACTIVE DYES CIBA-GEIGY CORPORATION (US) 1981-08-11 US disclosed
US-4033943-A Fiber reactive water soluble 2,4,6-triamino, 3-cyano pyridine-(5) azo dyestuffs CIBA-GEIGY CORPORATION (US) 1977-07-05 US disclosed