Sugi Predict

Sugi Predict / Compounds / SCHEMBL4903434

SCHEMBL4903434

SCHEMBL4903434

Nc1cccc(C(=O)Nc2ccc(S(=O)(=O)O)c(N)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 4/20 0.54
▸ ULK1 O75385 1/20 0.52
▸ CNR1 P21554 1/20 0.48
▸ HSD17B10 Q99714 2/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48
▸ HDAC3 O15379 1/20 0.47
▸ BRAF P15056 1/20 0.47
▸ HDAC4 P56524 1/20 0.47
▸ HDAC1 Q13547 1/20 0.47
▸ HDAC7 Q8WUI4 1/20 0.47
▸ HDAC2 Q92769 1/20 0.47
▸ HDAC10 Q969S8 1/20 0.47
▸ HDAC11 Q96DB2 1/20 0.47
▸ HDAC8 Q9BY41 1/20 0.47
▸ HDAC6 Q9UBN7 1/20 0.47
▸ HDAC9 Q9UKV0 1/20 0.47
▸ HDAC5 Q9UQL6 1/20 0.47
▸ ALDH1A1 P00352 2/20 0.47
▸ KDM4C Q9H3R0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4905086 0.89 PTGS1 (0.54) PTGS1ULK1CNR1HSD17B10SMN1; SMN2
SCHEMBL11239551 0.89 PTGS1 (0.56) PTGS1ULK1CNR1HSD17B10SMN1; SMN2
SCHEMBL10797547 0.88 MAOA (0.56) CNR1HSD17B10SMN1; SMN2ALDH1A1MEN1
SCHEMBL10803115 0.88 KCNK3 (0.58) SMN1; SMN2MEN1KMT2ATP53
SCHEMBL7555076 0.87 KCNK3 (0.54) SMN1; SMN2MEN1KMT2APRMT1SIRT1
SCHEMBL4905389 0.85 MEN1 (0.60) PTGS1SMN1; SMN2HDAC3BRAFHDAC4
SCHEMBL11438759 0.84 ULK1 (0.53) PTGS1ULK1CNR1HSD17B10SMN1; SMN2
SCHEMBL11435785 0.83 TNNI3 (0.54) PTGS1ULK1CNR1HSD17B10SMN1; SMN2
SCHEMBL11436263 0.83 CASP6 (0.51) PTGS1ULK1CNR1HSD17B10SMN1; SMN2
SCHEMBL10797525 0.82 PTGS1 (0.62) PTGS1ULK1CNR1HSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101731-B2 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORPORATION 2012-01-24 — — US disclosed
US-20100199443-A1 YELLO ANIONIC DISAZO DYES LENNARTZ MICHAEL 2010-08-12 — — US disclosed
US-7723494-B2 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 — — US disclosed
US-20080119643-A1 4,4'-Diazobenzanilide Dyestuffs LENNARTZ MICHAEL 2008-05-22 — — US disclosed
US-20080114158-A1 Yellow anionic disazo dyes LENNARTZ MICHAEL 2008-05-15 — — US disclosed
US-7341607-B2 Based on diaminobenzanilides or, more specifically (aminobenzoylamino),(sulfo-),(methoxy)anilines; stable aqueous solutions;nonbleeding/colorfastness; excellent degrees of exhaustion with high colour strength; dyeing natural or synthetic materials, particularly, paper; neutral or greenish-yellow hues CIBA SPECIALTY CHEMICALS CORP. (US) 2008-03-11 — — US disclosed
US-20080047079-A1 Reactive Polyazo Dyes DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-02-28 — — US disclosed
EP-0538785-B1 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AG (DE) 1997-04-09 — — EP disclosed
US-5349057-A Water soluble azo dyes containing a cyanoamino-triazinyl-amino group and a fiber-reactive of the sulfone series HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-20 — — US disclosed
EP-0511246-B1 WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST AG (DE) 1994-09-07 — — EP disclosed
US-5227475-A WATER-SOLUBLE FIBER-REACTIVE DYESTUFFS CONTAINING A CYANAMIDO-SUBSTITUTED TRIAZINYLAMINO-GROUPING, AND A PROCESS FOR DYEING WITH THE USE OF THESE DYES HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-13 — — US disclosed
EP-0538785-A2 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-28 — — EP disclosed
EP-0511246-A1 WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE. HOECHST AG (DE) 1992-11-04 — — EP disclosed
EP-0471713-A1 WATER-SOLUBLE AZO DYES, PROCESS FOR PRODUCING THEM AND THEIR USE. HOECHST AG (DE) 1992-02-26 — — EP disclosed
EP-0471702-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE. HOECHST AG (DE) 1992-02-26 — — EP disclosed
WO-1991010709-A1 WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-25 — — WO disclosed
US-5021558-A Color strength, fastness HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-04 — — US disclosed
WO-1990013603-A1 WATER-SOLUBLE AZO DYES, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-15 — — WO disclosed
WO-1990013604-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-15 — — WO disclosed
EP-0388864-A2 Water-soluble, fibre-reactive dyes, method of their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119643-A1 4,4'-Diazobenzanilide Dyestuffs CYP4B1, TYR, DDT PTGS1 2903/4885ULK1 3193/4885CNR1 2880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.