Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552286 | 0.82 | ALDH1A1 (0.56) | MAPTITGB1ITGA4KMT2AMEN1 | |
| SCHEMBL7554535 | 0.82 | ITGB1 (0.68) | MAPTITGB1ITGA4KMT2APOLB | |
| SCHEMBL7556321 | 0.77 | MAPT (0.63) | MAPTITGB1ITGA4KMT2AMEN1 | |
| SCHEMBL7554369 | 0.74 | ITGB1 (0.66) | MAPTITGB1ITGA4POLBTRPV1 | |
| Hydrochloric Acid SCHEMBL10839707 | 0.74 | MAPT (0.56) | MAPTKMT2AMEN1POLBTRPV1 | |
| SCHEMBL4865033 | 0.74 | TP53 (0.59) | MAPTKMT2AMEN1LMNA | |
| SCHEMBL9616913 | 0.72 | MAPT (0.54) | MAPTKMT2AMEN1POLBEPHX1 | |
| SCHEMBL8297736 | 0.72 | MAPT (0.74) | MAPTKMT2AMEN1POLBTRPV1 | |
| SCHEMBL3752386 | 0.71 | MAPT (0.72) | MAPTKMT2AMEN1POLBTRPV1 | |
| SCHEMBL7553920 | 0.71 | ITGB1 (0.58) | MAPTITGB1ITGA4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002055661-A2 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-07-18 | — | — | WO | claimed |
| WO-2002055661-A2 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-07-18 | — | — | WO | disclosed |