Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7555562 | 0.82 | MAPT (0.62) | LMNAPOLBCYP2C19MAPTTRPV1 | |
| SCHEMBL7558694 | 0.77 | KDR (0.59) | ALDH1A1LMNATSHRSMN1; SMN2MAPT | |
| SCHEMBL7554535 | 0.76 | ITGB1 (0.68) | ALDH1A1LMNAPOLBL3MBTL1CYP1A2 | |
| SCHEMBL8298095 | 0.76 | ALDH1A1 (0.58) | ALDH1A1LMNAPOLBL3MBTL1MAPT | |
| SCHEMBL20472469 | 0.76 | CHRNA7 (0.76) | ALDH1A1LMNAL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL29776952 | 0.76 | CHRNA7 (0.76) | ALDH1A1LMNAL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL3751466 | 0.75 | ALDH1A1 (0.57) | ALDH1A1LMNAPOLBL3MBTL1CYP1A2 | |
| SCHEMBL1013241 | 0.74 | ALDH1A1 (0.63) | ALDH1A1LMNAL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL27322095 | 0.74 | CHRNA7 (0.61) | ALDH1A1LMNAL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL9835452 | 0.74 | CHRNA7 (0.61) | ALDH1A1LMNAL3MBTL1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002055661-A2 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-07-18 | — | — | WO | claimed |
| WO-2002055661-A2 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-07-18 | — | — | WO | disclosed |