Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10220710 | 0.78 | MEN1 (0.60) | KDRMAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL7552286 | 0.77 | ALDH1A1 (0.56) | MAPTSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL118026 | 0.76 | KDR (1.00) | KDRPDK1GRM4 | |
| SCHEMBL29364392 | 0.76 | KDR (1.00) | KDRPDK1GRM4 | |
| SCHEMBL25574412 | 0.75 | KMT2A (0.65) | MAPTSMN1; SMN2CASP3GAAGRIN2B | |
| SCHEMBL2329430 | 0.74 | KDR (0.78) | KDRMAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL9835641 | 0.74 | KDR (0.78) | KDRMAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL10885507 | 0.74 | KDR (0.78) | KDRMAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL7556321 | 0.74 | MAPT (0.63) | MAPTSMN1; SMN2NPSR1LMNAHTT | |
| SCHEMBL25574313 | 0.73 | MEN1 (0.56) | KDRMAPTSMN1; SMN2NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002055661-A2 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-07-18 | — | — | WO | claimed |
| WO-2002055661-A2 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-07-18 | — | — | WO | disclosed |