SCHEMBL7557438

SCHEMBL7557438

CCOC(=O)c1ccc(CC(C(C)=O)C(=O)OC(C)(C)C)o1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
ALDH1A1 P00352 12/20 0.45
MAPT P10636 5/20 0.45
KDM4E B2RXH2 5/20 0.45
POLB P06746 2/20 0.45
TLR2 O60603 1/20 0.45
NSD2 O96028 1/20 0.45
PKM P14618 1/20 0.45
MPI P34949 1/20 0.45
GRK6 P43250 1/20 0.45
RECQL P46063 1/20 0.45
TLR1 Q15399 1/20 0.45
TLR6 Q9Y2C9 1/20 0.45
LMNA P02545 3/20 0.44
GAA P10253 2/20 0.44
TSHR P16473 5/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13269194 0.80 ALDH1A1 (0.56) L3MBTL1NPC1RAB9AHDAC4HDAC6
SCHEMBL7557461 0.78 KMT2A (0.47) NPC1RAB9AALDH1A1MAPTKDM4E
SCHEMBL8244760 0.77 L3MBTL1 (0.59) L3MBTL1NPC1RAB9AHDAC4HDAC6
SCHEMBL11545671 0.74 CA12 (0.42) NPC1RAB9AMAPTPOLBLMNA
SCHEMBL13021117 0.74 HDAC4 (0.56) L3MBTL1NPC1RAB9AHDAC4HDAC6
SCHEMBL151035 0.73 ALDH1A1 (0.60) L3MBTL1NPC1RAB9AHDAC4HDAC6
SCHEMBL13269180 0.73 HTT (0.55) L3MBTL1NPC1RAB9AALDH1A1MAPT
SCHEMBL6240522 0.72 ALDH1A1 (0.59) L3MBTL1NPC1RAB9AHDAC4HDAC6
SCHEMBL2093655 0.72 ALDH1A1 (0.58) L3MBTL1NPC1RAB9AHDAC4HDAC6
SCHEMBL8619631 0.72 CYP3A4 (0.47) MAPTLMNAGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882701-B1 SUBSTITUTED AMIDE DERIVATIVES BANYU PHARMA CO LTD (JP) 2002-07-24 EP disclosed
US-6048894-A FARNESYL-PROTEIN TRANSFERASE INHIBITORS, ANTITUMOR OR ANTICANCER AGENTS BANYU PHARMACEUTICAL CO., LTD. (JP) 2000-04-11 US disclosed
EP-0882701-A1 SUBSTITUTED AMIDE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1998-12-09 EP disclosed