Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557438 | 0.78 | L3MBTL1 (0.46) | KMT2AMEN1ALDH1A1CYP2C19LMNA | |
| SCHEMBL18161428 | 0.77 | RAB9A (0.61) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL18161442 | 0.74 | SMN1; SMN2 (0.54) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL7575343 | 0.72 | ALDH1A1 (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7557506 | 0.72 | SMN1; SMN2 (0.49) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL7576681 | 0.71 | ALDH1A1 (0.47) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7555918 | 0.71 | ALDH1A1 (0.51) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7057941 | 0.70 | MMP1 (0.48) | SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7492161 | 0.70 | LMNA (0.55) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7555657 | 0.70 | ALDH1A1 (0.43) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882701-B1 | SUBSTITUTED AMIDE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-6048894-A | FARNESYL-PROTEIN TRANSFERASE INHIBITORS, ANTITUMOR OR ANTICANCER AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0882701-A1 | SUBSTITUTED AMIDE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |