Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 13/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788388 | 0.80 | DPP4 (0.56) | GCGRDHODHDPP4 | |
| SCHEMBL8949698 | 0.79 | GCGR (0.56) | GCGRDPP4 | |
| SCHEMBL10411663 | 0.75 | EGLN1 (0.39) | GCGREGLN1MAPK14 | |
| SCHEMBL286403 | 0.75 | GABRA5 (0.52) | — | |
| SCHEMBL6956576 | 0.75 | GCGR (0.46) | GCGRDHODHDPP4 | |
| SCHEMBL17613419 | 0.74 | HMGCR (0.46) | GCGR | |
| SCHEMBL10410199 | 0.73 | EGLN1 (0.48) | EGLN1DHODH | |
| SCHEMBL10735986 | 0.72 | KDM4E (0.37) | EGLN1 | |
| SCHEMBL6590702 | 0.71 | EGLN1 (0.46) | GCGREGLN1DHODHMAPK14 | |
| SCHEMBL8846678 | 0.71 | ADORA2A (0.38) | GCGREGLN1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705837-B1 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-5744604-A | Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| US-5677455-A | Preparation of 3-oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0705837-A2 | Preparation of 3-Oxy-5-oxo-6-heptenoic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1996-04-10 | — | — | EP | disclosed |
| US-4929620-A | ANTILIPEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| US-4868185-A | HYPOLIPIDEMIC, ANTICHOLESTEROL | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | disclosed |