Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19260277 | 0.83 | HTR2A (0.50) | PGR | |
| SCHEMBL24795394 | 0.79 | PGR (0.57) | PGR | |
| SCHEMBL24794235 | 0.77 | PGR (0.60) | PGR | |
| SCHEMBL24794224 | 0.77 | RARB (0.60) | PGR | |
| SCHEMBL6771936 | 0.76 | PGR (0.68) | PGR | |
| SCHEMBL6770222 | 0.76 | PGR (0.64) | PGR | |
| SCHEMBL1396636 | 0.74 | HSPA9 (0.62) | PGR | |
| SCHEMBL24103467 | 0.74 | HTR2A (0.47) | PGR | |
| SCHEMBL31243558 | 0.73 | RARB (0.49) | — | |
| SCHEMBL6540476 | 0.73 | PGR (0.59) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175404-A1 | QUINAZOLINONE AND BENZOXAZINE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | American Home Products Corporation (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066560-A1 | QUINAZOLINONE AND BENZOXAZINE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |