Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 12/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4420052 | 0.87 | PLA2G7 (0.67) | PLA2G7MAPTDAO | |
| SCHEMBL4425973 | 0.87 | PLA2G7 (0.59) | PLA2G7ALDH1A1LMNAHPGDGFER | |
| SCHEMBL3545058 | 0.82 | PLA2G7 (0.71) | PLA2G7ALDH1A1LMNAHPGDGFER | |
| SCHEMBL7585604 | 0.81 | PLA2G7 (0.78) | PLA2G7ALDH1A1LMNAHPGDGFER | |
| SCHEMBL7557792 | 0.80 | PLA2G7 (0.50) | PLA2G7 | |
| SCHEMBL4423257 | 0.80 | PLA2G7 (0.76) | PLA2G7MAOBDAO | |
| SCHEMBL4418525 | 0.79 | PLA2G7 (1.00) | PLA2G7MAOBMAPTDAO | |
| SCHEMBL4415191 | 0.79 | PLA2G7 (0.74) | PLA2G7LMNAHPGDMAOBMAPT | |
| SCHEMBL3545647 | 0.79 | PLA2G7 (0.67) | PLA2G7ALDH1A1LMNAHPGDGFER | |
| SCHEMBL4423080 | 0.78 | PLA2G7 (0.72) | PLA2G7MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173424-A1 | PYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066566-A1 | PYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-09 | — | — | WO | disclosed |