Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27980060 | 0.77 | AGTR1 (0.35) | TLR8ALDH1A1CA2KMT2APOLB | |
| Acetic Acid SCHEMBL28899029 | 0.76 | AGTR1 (0.35) | TLR8ALDH1A1CA2KMT2APOLB | |
| SCHEMBL27845254 | 0.75 | TLR8 (0.42) | TLR8ALDH1A1KMT2APOLBCYP3A4 | |
| SCHEMBL27959808 | 0.74 | KCNH2 (0.40) | TLR8ALDH1A1KMT2APOLBCYP3A4 | |
| SCHEMBL4314338 | 0.74 | SMN1; SMN2 (0.39) | TLR8ALDH1A1KMT2APOLBARG1 | |
| SCHEMBL5089381 | 0.73 | ALDH1A1 (0.38) | TLR8ALDH1A1KMT2APOLBCYP3A4 | |
| 2-Ethylhexanoic Acid SCHEMBL28899013 | 0.73 | CA2 (0.47) | ALDH1A1CA2KMT2ACA1ARG1 | |
| SCHEMBL28164150 | 0.72 | KCNH2 (0.39) | TLR8ALDH1A1KMT2APOLBCHRM2 | |
| SCHEMBL28813866 | 0.72 | ALDH1A1 (0.33) | ALDH1A1CA2KMT2ACYP3A4TSHR | |
| SCHEMBL21514090 | 0.71 | TLR8 (0.41) | TLR8ALDH1A1KMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222916-A2 | Use of amino-alcohol derivatives containing a urea function as moisturiser in cosmetic or dermatological compositions | L'OREAL (FR) | 2002-07-17 | — | — | EP | disclosed |