SCHEMBL7558007

SCHEMBL7558007

CC(C)(C)[Si](C)(C)OC(=O)c1cc(O[Si](C)(C)C(C)(C)C)cc(O[Si](C)(C)C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.39
CA1 P00915 4/20 0.39
CA9 Q16790 4/20 0.39
PREP P48147 4/20 0.35
KDM4E B2RXH2 3/20 0.33
MAPT P10636 2/20 0.33
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
GAA P10253 1/20 0.33
HDAC3 O15379 2/20 0.31
HDAC4 P56524 2/20 0.31
HDAC1 Q13547 2/20 0.31
HDAC7 Q8WUI4 2/20 0.31
HDAC2 Q92769 2/20 0.31
HDAC10 Q969S8 2/20 0.31
HDAC11 Q96DB2 2/20 0.31
HDAC8 Q9BY41 2/20 0.31
HDAC6 Q9UBN7 2/20 0.31
HDAC9 Q9UKV0 2/20 0.31
HDAC5 Q9UQL6 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18540677 0.91 NOTUM (0.38) CA12CA1CA9PREPHSP90AA1
SCHEMBL6625609 0.86 KDM4E (0.44) CA12CA1CA9PREPKDM4E
SCHEMBL2982620 0.84 ESR1 (0.42) CA12CA1CA9KDM4EHSP90AA1
SCHEMBL18304558 0.83 KDM4E (0.44) CA12CA1CA9KDM4EMAPT
SCHEMBL1604136 0.83 PREP (0.44) CA12CA1CA9PREPMAPT
SCHEMBL6155680 0.82 PLA2G2A (0.41) CA12CA1CA9PREP
SCHEMBL6114920 0.82 CA12 (0.41) CA12CA1CA9PREPMAPT
SCHEMBL29831305 0.81 CA12 (0.40) CA12CA1CA9PREPKDM4E
SCHEMBL25665190 0.80 RXRA (0.46) CA12CA1CA9KDM4EGAA
SCHEMBL8818840 0.79 CA1 (0.58) CA12CA1CA9PREPKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10975307-B2 Liquid crystalline epoxy compound with terminal mesogen connected by flexible linkage and method for preparing the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2021-04-13 US disclosed
US-20180201835-A1 LIQUID CRYSTALLINE EPOXY COMPOUND WITH TERMINAL MESOGEN CONNECTED BY FLEXIBLE LINKAGE AND METHOD FOR PREPARING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-07-19 US disclosed
EP-1222219-A1 SELF-ASSEMBLING COMPOUNDS AND USE OF THE SAME TO INDUCE ORDER IN ORGANIC MEDIA Northwestern University (US) 2002-07-17 EP disclosed
WO-2001021678-A1 SELF-ASSEMBLING COMPOUNDS AND USE OF THE SAME TO INDUCE ORDER IN ORGANIC MEDIA NORTHWESTERN UNIVERSITY (US) 2001-03-29 WO disclosed