SCHEMBL7558013

SCHEMBL7558013

CC(C)(C)[Si](C)(C)Oc1cc(O[Si](C)(C)C(C)(C)C)cc(C(=O)O)c1.C[SiH](C)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.36
CA1 P00915 6/20 0.36
CA12 O43570 5/20 0.36
CA9 Q16790 5/20 0.36
RXRA P19793 2/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
PREP P48147 2/20 0.33
CA2 P00918 2/20 0.33
HPGD P15428 1/20 0.33
TPMT P51580 1/20 0.32
NR4A2 P43354 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
CA3 P07451 1/20 0.32
PKM P14618 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6155680 0.92 PLA2G2A (0.41) PLA2G2ACA1CA12CA9RXRA
SCHEMBL3296656 0.89 CA12 (0.41) PLA2G2ACA1CA12CA9MEN1
SCHEMBL25665190 0.86 RXRA (0.46) CA1CA12CA9RXRACA2
SCHEMBL6654531 0.81 TPMT (0.48) PLA2G2ACA1CA12CA9RXRA
SCHEMBL6542930 0.78 CA1 (0.52) CA1CA12CA9RXRAKMT2A
SCHEMBL6114920 0.78 CA12 (0.41) CA1CA12CA9MEN1KMT2A
SCHEMBL29831305 0.77 CA12 (0.40) CA1CA12CA9PREP
SCHEMBL18120875 0.76 CA12 (0.38) CA1CA12CA9PREP
SCHEMBL2989104 0.76 AKR1C3 (0.53) CA1CA12CA9RXRAKMT2A
SCHEMBL6625609 0.76 KDM4E (0.44) CA1CA12CA9PREPCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1222219-A1 SELF-ASSEMBLING COMPOUNDS AND USE OF THE SAME TO INDUCE ORDER IN ORGANIC MEDIA Northwestern University (US) 2002-07-17 EP disclosed
WO-2001021678-A1 SELF-ASSEMBLING COMPOUNDS AND USE OF THE SAME TO INDUCE ORDER IN ORGANIC MEDIA NORTHWESTERN UNIVERSITY (US) 2001-03-29 WO disclosed