Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 7/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | RARG | P13631 | 2/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2701032 | 0.90 | KDM4E (0.55) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL29717125 | 0.90 | KDM4E (0.55) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL18288087 | 0.84 | NPC1 (0.51) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7558052 | 0.81 | CDC25B (0.57) | HPGDALDH1A1NPC1RAB9APOLB | |
| Benzophenone SCHEMBL28424466 | 0.79 | HPGD (0.89) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL34895 | 0.79 | MAPT (0.53) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL30898565 | 0.79 | MAPT (0.53) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL6113239 | 0.79 | MAPT (0.61) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL33368 | 0.78 | NPC1 (0.77) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL30504311 | 0.77 | LCK (0.56) | HPGDALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052354-A1 | Paramagnetic DOTA derivatives, pharmaceutical agents that contain the latter, process for their production, and their use for MR imaging of necrosis and infarction | SCHERING AG | 2002-05-02 | — | — | US | disclosed |
| WO-2001051095-A2 | PARAMAGNETIC DOTA DERIVATIVES, PHARMACEUTICAL AGENTS CONTAINING THE SAME, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE FOR THE MR IMAGING OF NECROSIS AND INFARCTION | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052354-A1 | Paramagnetic DOTA derivatives, pharmaceutical agents that contain the latter, process for their production, and their use for MR imaging of necrosis and infarction | TNNI3, NPR1, LPXN | HPGD 58/4885ALDH1A1 3405/4885MAPT 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.