SCHEMBL755824

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL755050	0.83	SLC6A2 (0.41)	SLC6A2SLC6A4SLC6A3CHRNB4CHRNA3
	SCHEMBL28110010	0.81	SLC6A2 (0.46)	SLC6A2SLC6A4SLC6A3LMNATDP1
	SCHEMBL7448777	0.81	HTR2A (0.45)	ENPP2CHRNB4CHRNA3PRSS1PRSS2
	SCHEMBL11888529	0.77	ENPP2 (0.45)	S1PR1ENPP2PRSS1PRSS2PRSS3
	SCHEMBL3279344	0.77	HDAC4 (0.47)	S1PR1ENPP2PRSS1PRSS2PRSS3
	SCHEMBL16191365	0.77	SMN1; SMN2 (0.45)	SLC6A2SLC6A4SLC6A3DDB1CRBN
	SCHEMBL23923595	0.77	ADRB1 (0.50)	SLC6A2SLC6A4SLC6A3DRD3TSHR
	SCHEMBL30317791	0.77	ADRB1 (0.50)	SLC6A2SLC6A4SLC6A3DRD3TSHR
	SCHEMBL23923596	0.77	ADRB1 (0.50)	SLC6A2SLC6A4SLC6A3DRD3TSHR
	SCHEMBL19759679	0.76	ENPP2 (0.44)	S1PR1ENPP2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.