Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | AKT1 | P31749 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.69 |
| ▸ | PRKCG | P05129 | 1/20 | 0.69 |
| ▸ | PRKCB | P05771 | 1/20 | 0.69 |
| ▸ | PRKCA | P17252 | 1/20 | 0.69 |
| ▸ | PRKCH | P24723 | 1/20 | 0.69 |
| ▸ | PRKCI | P41743 | 1/20 | 0.69 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.69 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.69 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.69 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.69 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | GMNN | O75496 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203174 | 1.00 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AAKT1LMNA | |
| SCHEMBL2126087 | 1.00 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AAKT1LMNA | |
| SCHEMBL29733465 | 0.99 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2AAKT1LMNA | |
| SCHEMBL29394546 | 0.97 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AAKT1LMNA | |
| SCHEMBL53200 | 0.97 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AAKT1LMNA | |
| SCHEMBL29365750 | 0.97 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AAKT1LMNA | |
| SCHEMBL29905581 | 0.97 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AAKT1LMNA | |
| SCHEMBL94022 | 0.90 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AAKT1LMNA | |
| SCHEMBL93475 | 0.90 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AAKT1LMNA | |
| SCHEMBL1532761 | 0.90 | AKT1 (0.83) | ALDH1A1MEN1KMT2AAKT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020177723-A1 | Compounds and methods for the treatment of inflammatory and immune disorders | LEUKOSITE, INC. | 2002-11-28 | — | — | US | disclosed |
| US-6294574-B1 | THERAPY OF DISORDER CAUSED BY PLATELET ACTIVATION FACTOR BY TRANS-2-(5-N'-METHYL-N'-HYDROXYUREIDYLMETHYL)-3-METHOXY-4-P-CH LOROPHENYLTHIOETHOXPHENYL)-5-(3,4,5-TRIMETHOXPHENYL)TETRAHYDRO FURAN OR ITS SALT | CYTOMED, INC. | 2001-09-25 | — | — | US | disclosed |
| US-6201016-B1 | IMMUNOSUPPRESSANT AS 5-LIPOXYGENASE INHIBITOR AND/OR AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONIST | CYTOMED INCORPORATED | 2001-03-13 | — | — | US | disclosed |
| EP-0650485-B1 | 2,5-DIARYL TETRAHYDRO-THIOPHENES, -FURANS AND ANALOGS FOR THE TREATMENT OF INFLAMMATORY AND IMMUNE DISORDERS | CYTOMED INC (US) | 2000-10-11 | — | — | EP | disclosed |
| US-5856323-A | PAF RECEPTOR ANTAGONISTS, INHIBITING THE ENZYME 5-LIPOXYGENASE | CYTOMED, INC. (US) | 1999-01-05 | — | — | US | disclosed |
| US-5792776-A | HYDROXAMIC SUBSTITUTED TETRAHYDROTHIPOHENES, TETRAHYDROFURANS, PYRROLIDINES AND CYCLOPENTANES | CYTOMED, INC., (US) | 1998-08-11 | — | — | US | disclosed |
| US-5780503-A | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders | CYTOMED, INC. (US) | 1998-07-14 | — | — | US | disclosed |
| US-5681966-A | ENANTIOMERICALLY ENRICHED DISUBSTITUTED TETRAHYDROFURANS, TETRAHYDROTHIOPHENES ACT AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS OR 5-LIPOXYGENASE INHIBITORS | CYTOMED, INC. (US) | 1997-10-28 | — | — | US | disclosed |
| US-5648486-A | LIPOXYGENASE INHIBITORS | CYTOMED, INC. (US) | 1997-07-15 | — | — | US | disclosed |
| US-5434151-A | Treatment of immune and inflammatory disorders, aryl substituted tetrahydrofurans, tetrahydrothiophenes, cyclopentanes, pyrrolidines | CYTOMED, INC. (US) | 1995-07-18 | — | — | US | disclosed |
| EP-0656004-A1 | DUAL FUNCTIONAL ANTI-INFLAMMATORY AND IMMUNOSUPPRESSIVE AGENTS | CYTOMED, INC. (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0650485-A1 | 2,5-DIARYL TETRAHYDRO-THIOPHENES, -FURANS AND ANALOGS FOR THE TREATMENT OF INFLAMMATORY AND IMMUNE DISORDERS | CYTOMED, INC. (US) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994006790-A1 | 2,4-DIARYL-1,3-DITHIOLANES; 2,4-DIARYL-1,3-DIOXOLANES; 2,4-DIARYL-1,3-OXATHIOLANES; AND 2,5-DIARYL-1,3-OXATHIOLANES AS PAF RECEPTOR ANTGONISTS AND INHIBITORS OF 5-LIPOXYGENASE | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1994-03-31 | — | — | WO | disclosed |
| WO-1994004537-A2 | DUAL FUNCTIONAL ANTI-INFLAMMATORY AND IMMUNOSUPPRESSIVE AGENTS | CYTOMED, INC. (US) | 1994-03-03 | — | — | WO | disclosed |
| WO-1994001430-A1 | 2,5-DIARYL TETRAHYDRO-THIOPHENES, -FURANS AND ANALOGS FOR THE TREATMENT OF INFLAMMATORY AND IMMUNE DISORDERS | CYTOMED, INC. (US) | 1994-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177723-A1 | Compounds and methods for the treatment of inflammatory and immune disorders | LTB4R2, LTC4S, LTB4R | ALDH1A1 556/4885MEN1 4875/4885KMT2A 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.