SCHEMBL7558647

SCHEMBL7558647

CCCP(C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ESR1 P03372 4/20 0.38
ESR2 Q92731 4/20 0.38
TP53 P04637 1/20 0.36
KCNN4 O15554 1/20 0.33
SIGMAR1 Q99720 1/20 0.32
PSIP1 O75475 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30
PCSK9 Q8NBP7 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
LTA4H P09960 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13391635 0.87 CYP3A4 (0.45) CYP3A4TDP1ESR1ESR2TP53
SCHEMBL9441831 0.87 CYP3A4 (0.45) CYP3A4TDP1ESR1ESR2TP53
SCHEMBL30145249 0.87 HPGD (0.40) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL4750482 0.86 LTA4H (0.36) CYP3A4TDP1ESR1ESR2TP53
SCHEMBL11115959 0.84 LTA4H (0.37) CYP3A4TDP1ESR1ESR2TP53
SCHEMBL15659608 0.82 DNM1 (0.39) TP53SIGMAR1CES2CES1LTA4H
Iodide SCHEMBL491999 0.82 CYP3A4 (0.41) CYP3A4TDP1ESR1ESR2TP53
SCHEMBL9492996 0.82 CYP3A4 (0.41) CYP3A4TDP1ESR1ESR2TP53
Bromide SCHEMBL493074 0.82 CYP3A4 (0.41) CYP3A4TDP1ESR1ESR2TP53
Hydrochloric Acid SCHEMBL493348 0.82 TDP1 (0.41) CYP3A4TDP1ESR1ESR2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3527639-B1 A METHOD FOR BONDING A THERMOPLASTIC MATERIAL BY MICROWAVE-IRRADIATION PROIONIC GMBH (AT) 2021-09-08 EP claimed
CN-112209967-B Chiral spiro monophosphine-oxazoline ligand and preparation method thereof 浙江九洲药业股份有限公司 2025-03-04 CN disclosed
EP-3527639-B1 A METHOD FOR BONDING A THERMOPLASTIC MATERIAL BY MICROWAVE-IRRADIATION PROIONIC GMBH (AT) 2021-09-08 EP disclosed
CN-112209967-A Chiral spiro monophosphine-oxazoline ligand and preparation method thereof 瑞博(杭州)医药科技有限公司 2021-01-12 CN disclosed
CN-111909206-A Chiral spiro monophosphine ligand and preparation method thereof 浙江瑞博制药有限公司 2020-11-10 CN disclosed
US-6492532-B2 Method for producing carbonyl compound by dehydrogenating alcohol MITSUBISHI CHEMICAL CORPORATION (JP) 2002-12-10 US disclosed
US-20020002289-A1 Method for producing carbonyl compound by dehydrogenating alcohol MITSUBISHI CHEMICAL CORPORATION (JP) 2002-01-03 US disclosed
EP-1160245-A1 PROCESS FOR PRODUCING CARBONYL COMPOUNDS BY DEHYDROGENATION OF ALCOHOLS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-12-05 EP disclosed
EP-0531174-B1 Oligomerization catalyst for alpha-olefins and process for oligomerizing alpha-olefins MITSUI PETROCHEMICAL IND (JP) 1995-06-21 EP disclosed
US-5286695-A Oligomerization catalyst for α-olefins and process for oligomerizing α-olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-02-15 US disclosed
US-4265827-A METHYLCYCOHEXYL-O-ANISYLARSINE OPTICALLY ACTIVE CATALYST MONSANTO COMPANY (US) 1981-05-05 US disclosed
US-4261919-A OF BETA-SUBSTITUTED-ALPHA-ACYLAMIDO-ACRYLIC ACIDS TO YIELD OPTICALLY ACTIVE MIXTURE MONSANTO COMPANY (US) 1981-04-14 US disclosed
US-4255595-A Optically active cyclooctenyl ethyl alcohol STUDIENGESELLSCHAFT KOHLE MBH (DE) 1981-03-10 US disclosed
US-4155946-A CATALYST CONSISTS OF A NICKEL COMPOUND, A TRIALKYL ALUMINUM COMPOUND; PHOSPHOROUS COMPOUND AND A HALOGENATED PHENOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-05-22 US disclosed
US-4152366-A POLYMERIZABLE TO OPTICALLY ACTIVE POLYMERS STUDIENGESELLSCHAFT KOHLE MBH (DE) 1979-05-01 US disclosed
US-4124533-A HYDROGENATION CATALYSTS MONSANTO COMPANY (US) 1978-11-07 US disclosed
US-4119652-A HYDROGENATION CATALYSTS; COORDINATION COMPOUNDS OF IRIDIUM, RHODIUM OR RUTHENIUM WITH PHOSPHINE OR ARSINE LIGANDS; OPTICALLY ACTIVE MONSANTO COMPANY (US) 1978-10-10 US disclosed
US-4098834-A Optically active 3-substituted cyclooctene bicyclo-[6.0.3.]-undecene-3 and exo-2-vinyl norbornane STUDIENGESELLSCHAFT KOHLE MBH (DE) 1978-07-04 US disclosed
US-4096250-A ANTI-ARTHRITIC SMITHKLINE CORPORATION (US) 1978-06-20 US disclosed
US-3978147-A NI, LEWIS ACID, PHOSPHINE STUDIENGESELLSCHAFT KOHLE M.B.H (DT) 1976-08-31 US disclosed