Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558647 | 0.87 | CYP3A4 (0.39) | HPGDALDH1A1KDM4ECYP3A4TDP1 | |
| SCHEMBL9441831 | 0.74 | CYP3A4 (0.45) | ALDH1A1KCNH2KDM4ECYP3A4TDP1 | |
| SCHEMBL13391635 | 0.74 | CYP3A4 (0.45) | ALDH1A1KCNH2KDM4ECYP3A4TDP1 | |
| SCHEMBL4750482 | 0.74 | LTA4H (0.36) | SMN1; SMN2KDM4ECYP3A4TDP1ESR1 | |
| SCHEMBL11115959 | 0.72 | LTA4H (0.37) | SMN1; SMN2KCNH2KMT2APKMMAPK1 | |
| Biphenyl SCHEMBL967556 | 0.71 | ALDH1A1 (0.64) | HPGDSMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL15659608 | 0.71 | DNM1 (0.39) | SMN1; SMN2KCNH2KMT2APKMMAPK1 | |
| SCHEMBL7902244 | 0.70 | TP53 (0.32) | — | |
| Iodide SCHEMBL491999 | 0.70 | CYP3A4 (0.41) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL9492996 | 0.70 | CYP3A4 (0.41) | CYP3A4TDP1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4073080-A1 | PROCESS FOR INDUSTRIAL PREPARATION OF THE DISODIUM SALT OF ((2S)-3-([1,1'-BIPHENYL]-4-YL)-2-((HYDROXY((1R)-1-(((1-(ISOBUTYRYLOXY)ETHOXY)CARBONYL)AMINO)ETHYL)PHOSPHORYL)METHYL)PROPANOYL)-L-ALANINE | Pharmaleads (FR) | 2022-10-19 | — | — | EP | disclosed |