Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.37 |
| ▸ | KDM4A | O75164 | 11/20 | 0.37 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.37 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7555162 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CHRNB2CHRNB4CHRNA4HTT | |
| SCHEMBL2537508 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CHRNB2CHRNB4CHRNA4HTT | |
| SCHEMBL2540699 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CHRNB2CHRNB4CHRNA4HTT | |
| SCHEMBL1415984 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CHRNB2CHRNB4CHRNA4HTT | |
| SCHEMBL7555488 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CHRNB2CHRNB4CHRNA4HTT | |
| SCHEMBL497714 | 0.98 | ALDH1A1 (0.58) | ALDH1A1CHRNB2CHRNB4CHRNA4HTT | |
| SCHEMBL497804 | 0.90 | — | — | |
| SCHEMBL3189950 | 0.87 | ALDH1A1 (0.70) | ALDH1A1CHRNB2CHRNB4CHRNA4HTT | |
| SCHEMBL131476 | 0.84 | ALDH1A1 (0.74) | ALDH1A1CHRNB2CHRNB4CHRNA4HTT | |
| SCHEMBL10699897 | 0.84 | ALOX5 (0.47) | ALDH1A1KDM4CKDM4AKDM5APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |