Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13164212 | 0.89 | METAP1 (0.38) | METAP1ALDH1A1TDP1TSHROPRM1 | |
| SCHEMBL19669824 | 0.86 | ALDH1A1 (0.37) | METAP1ALDH1A1TDP1TSHR | |
| SCHEMBL21227242 | 0.86 | ALDH1A1 (0.37) | METAP1ALDH1A1TDP1TSHR | |
| SCHEMBL24484137 | 0.86 | ALDH1A1 (0.37) | METAP1ALDH1A1TDP1TSHR | |
| SCHEMBL26736851 | 0.86 | ALDH1A1 (0.37) | METAP1ALDH1A1TDP1TSHR | |
| SCHEMBL22985766 | 0.82 | ALDH1A1 (0.44) | METAP1ALDH1A1TDP1TSHROPRM1 | |
| SCHEMBL7322881 | 0.82 | TSHR (0.44) | METAP1ALDH1A1TDP1TSHR | |
| SCHEMBL24512182 | 0.80 | OPRM1 (0.46) | ALDH1A1TDP1TSHROPRM1 | |
| SCHEMBL19295651 | 0.80 | GABBR2 (0.37) | ALDH1A1 | |
| SCHEMBL5932767 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472553-B1 | REACTING ACRYLONITRILE WITH CYCLOALIPHATIC VICINAL DIAMINES IN THE PRESENCE OF WATER AND AN ACID CATALYST WITH PKA OF -3.0-7. 5 | AIR PRODUCTS AND CHEMICALS, INC. | 2002-10-29 | — | — | US | disclosed |
| US-20020156315-A1 | SYNTHESIS OF NEW POLYNITRILES FROM CYCLOALIPHATIC VICINAL PRIMARY DIAMINES | BURDENIUC JUAN JESUS (US) | 2002-10-24 | — | — | US | disclosed |
| US-6433212-B1 | COMPOUNDS WITH SECONDARY AMINE AND NITRILE GROUPS | AIR PRODUCTS AND CHEMICALS, INC. | 2002-08-13 | — | — | US | disclosed |
| EP-1229021-A1 | Synthesis of new polynitriles from cycloaliphatic vicinal primary diamines | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156315-A1 | SYNTHESIS OF NEW POLYNITRILES FROM CYCLOALIPHATIC VICINAL PRIMARY DIAMINES | PNKP, PKN1, PARP1 | METAP1 1400/4885ALDH1A1 1772/4885TDP1 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.