Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.43 |
| ▸ | RXRG | P48443 | 13/20 | 0.43 |
| ▸ | RXRB | P28702 | 12/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 4/20 | 0.36 |
| ▸ | RARG | P13631 | 4/20 | 0.36 |
| ▸ | RARA | P10276 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560408 | 0.86 | RXRA (0.49) | RXRARXRGRXRBCYP3A4RARB | |
| SCHEMBL6472984 | 0.76 | CYP26A1 (0.46) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL6473142 | 0.75 | RXRA (0.36) | RXRARXRGRXRBCYP3A4RARB | |
| SCHEMBL7573999 | 0.73 | RXRA (0.41) | RXRARXRGRXRBCYP3A4RARB | |
| SCHEMBL7558937 | 0.72 | RXRA (0.48) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7558942 | 0.72 | RXRA (0.48) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7562932 | 0.71 | RXRA (0.40) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7562936 | 0.71 | RXRA (0.40) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7559396 | 0.70 | RXRA (0.47) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL8014334 | 0.66 | RXRA (0.60) | RXRARXRGRXRBCYP3A4RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986537-B1 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2002-08-07 | — | — | EP | claimed |