Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258705 | 0.82 | ALDH1A1 (0.42) | ALDH1A1GAAMAPTTDP1POLB | |
| SCHEMBL8918996 | 0.79 | TDP1 (0.42) | ALDH1A1GAAMAPTTDP1HPGD | |
| SCHEMBL28033756 | 0.74 | POLB (0.37) | ALDH1A1GAAMAPTPOLB | |
| SCHEMBL9645439 | 0.74 | SIRT1 (0.40) | POLBTRPV1SIRT1 | |
| SCHEMBL1224647 | 0.74 | TDP1 (0.34) | ALDH1A1MAPTTDP1HPGD | |
| SCHEMBL2903703 | 0.73 | PNMT (0.38) | ALDH1A1GAAMAPTTDP1 | |
| Ammonia Solution, Strong SCHEMBL7560640 | 0.72 | TDP1 (0.33) | ALDH1A1MAPTTDP1HPGD | |
| SCHEMBL28200857 | 0.72 | MAPT (0.49) | ALDH1A1GAAMAPTPOLB | |
| SCHEMBL20094597 | 0.72 | MAPT (0.45) | ALDH1A1GAAMAPTPOLB | |
| SCHEMBL583883 | 0.71 | HSPA5 (0.41) | ALDH1A1GAAMAPTTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173414-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064864-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |