Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18378463 | 0.82 | TSHR (0.48) | SMN1; SMN2TSHRALOX15HTTPOLB | |
| SCHEMBL7522860 | 0.77 | HSD17B10 (0.47) | SMN1; SMN2TSHRALOX15TP53MEN1 | |
| SCHEMBL6028292 | 0.75 | POLB (0.42) | SMN1; SMN2TSHRPOLBGAATHRB | |
| SCHEMBL20484557 | 0.75 | HTT (0.49) | SMN1; SMN2TSHRALOX15HTTPOLB | |
| SCHEMBL761922 | 0.73 | ALOX15 (0.45) | SMN1; SMN2TSHRALOX15HTTPOLB | |
| SCHEMBL20546526 | 0.72 | POLB (0.45) | SMN1; SMN2TSHRPOLBTP53GAA | |
| SCHEMBL19892686 | 0.70 | L3MBTL1 (0.40) | SMN1; SMN2TSHRPOLBGAAMEN1 | |
| SCHEMBL7503707 | 0.69 | POLB (0.48) | SMN1; SMN2TSHRALOX15HTTPOLB | |
| SCHEMBL18186741 | 0.69 | POLB (0.47) | SMN1; SMN2TSHRALOX15HTTPOLB | |
| SCHEMBL28343287 | 0.69 | GAA (0.49) | SMN1; SMN2TSHRPOLBTP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816342-B1 | Process for producing 1-substituted-hydantoins | SUMITOMO CHEMICAL CO (JP) | 2002-02-27 | — | — | EP | disclosed |
| US-5883260-A | Process for producing 1-substituted-hydantoins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0816342-A2 | Process for producing 1-substituted-hydantoins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-01-07 | — | — | EP | disclosed |