SCHEMBL28343287

SCHEMBL28343287

CCOC(=O)N(CC)c1ccccn1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
THRB P10828 1/20 0.47
POLB P06746 3/20 0.47
LMNA P02545 3/20 0.46
TP53 P04637 2/20 0.46
TSHR P16473 1/20 0.46
TRPM8 Q7Z2W7 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18378463 0.86 TSHR (0.48) GAASMN1; SMN2MEN1KMT2ATHRB
SCHEMBL18186741 0.84 POLB (0.47) GAASMN1; SMN2MEN1KMT2ATHRB
SCHEMBL9069781 0.84 LMNA (0.48) GAASMN1; SMN2MEN1KMT2APOLB
SCHEMBL16415718 0.83 LMNA (0.47) GAASMN1; SMN2MEN1KMT2APOLB
SCHEMBL666126 0.82 OPRM1 (0.53) GAASMN1; SMN2MEN1KMT2ATHRB
SCHEMBL9069782 0.82 POLB (0.48) GAASMN1; SMN2MEN1KMT2ATHRB
SCHEMBL5508940 0.82 POLB (0.60) GAASMN1; SMN2MEN1KMT2ATHRB
SCHEMBL23355845 0.81 MEN1 (0.51) GAASMN1; SMN2MEN1KMT2ATHRB
SCHEMBL5141980 0.81 MEN1 (0.51) GAASMN1; SMN2MEN1KMT2ATHRB
SCHEMBL2562392 0.80 POLB (0.51) GAASMN1; SMN2MEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110621678-A Antitumor compounds 法马马有限公司 2019-12-27 CN disclosed