Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.59 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.59 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.59 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.59 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.53 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951845 | 0.95 | GAA (0.68) | GAAHTTPRKAG1PRKAA2PRKAA1 | |
| SCHEMBL9720968 | 0.94 | GAA (0.66) | GAAHTTPRKAG1PRKAA2PRKAA1 | |
| SCHEMBL6757262 | 0.94 | GAA (0.66) | GAAHTTPRKAG1PRKAA2PRKAA1 | |
| SCHEMBL8637242 | 0.90 | GAA (0.74) | GAAHTTPRKAG1PRKAA2PRKAA1 | |
| SCHEMBL2842625 | 0.83 | GAA (0.59) | GAAHTTPRKAG1PRKAA2PRKAA1 | |
| SCHEMBL8863133 | 0.82 | GAA (1.00) | GAAHTTPRKAG1PRKAA2PRKAA1 | |
| SCHEMBL9288400 | 0.82 | PRKAG1 (0.61) | GAAHTTPRKAG1PRKAA2PRKAA1 | |
| SCHEMBL13804897 | 0.82 | GAA (0.58) | GAAHTTPRKAG1PRKAA2PRKAA1 | |
| SCHEMBL11139248 | 0.82 | GAA (0.48) | GAAHTTPRKAG1PRKAA2PRKAA1 | |
| SCHEMBL9887037 | 0.81 | GAA (0.58) | GAAHTTPRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6464901-B1 | IN AQUEOUS SYSTEMS BEING TREATED WITH A HALOGEN BIOCIDE; NONHALOGENATED, NITROGEN CONTAINING, AROMATIC COMPOUNDS; PROVIDING SUBSTITUTION FOR THE HYDROGENS OF THE BENZENE RING OF A BENZOTRIAZOLE | BL TECHNOLOGIES, INC. | 2002-10-15 | — | — | US | disclosed |
| EP-1190112-A1 | HALOGEN RESISTANT CORROSION INHIBITORS | BetzDearborn Inc (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000061836-A1 | HALOGEN RESISTANT CORROSION INHIBITORS | BETZDEARBORN INC. (US) | 2000-10-19 | — | — | WO | disclosed |
| EP-0399732-B1 | Benzimidazole derivatives | ZENECA LTD (GB) | 1995-07-26 | — | — | EP | disclosed |
| US-5171748-A | For hypertension, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-15 | — | — | US | disclosed |
| EP-0400835-A1 | Substituted benzimidazoles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0399732-A1 | Benzimidazole derivatives | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |