Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29055433 | 1.00 | TSHR (0.41) | TSHRALDH1A1CA2RAB9ASLC6A3 | |
| SCHEMBL24882533 | 0.89 | — | — | |
| SCHEMBL24882534 | 0.86 | HDAC4 (0.37) | TSHRMAPTCYP19A1SMN1; SMN2GAA | |
| SCHEMBL11804128 | 0.82 | TSHR (0.40) | TSHRALDH1A1CA2RAB9ASLC6A3 | |
| SCHEMBL13311339 | 0.77 | SMN1; SMN2 (0.41) | TSHRALDH1A1CA2RAB9ASLC6A3 | |
| SCHEMBL28546410 | 0.76 | LMNA (0.43) | ALDH1A1RAB9AMAPTKMT2ACYP19A1 | |
| SCHEMBL30151912 | 0.73 | CYP19A1 (0.43) | ALDH1A1CA2KDM4EKMT2ACYP19A1 | |
| SCHEMBL31650964 | 0.72 | ALDH1A1 (0.56) | TSHRALDH1A1CA2RAB9ASLC6A3 | |
| SCHEMBL9361337 | 0.72 | ALDH1A1 (0.39) | TSHRALDH1A1CA2RAB9ASLC6A3 | |
| SCHEMBL9303316 | 0.72 | ALDH1A1 (0.43) | TSHRALDH1A1CA2RAB9ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127043-A1 | STEREOSELECTIVE PROCESS FOR PREPARING (CYCLO)ALKYL PHENYLGLYCOLIC ACIDS | Sepracor Inc. (US) | 2001-08-29 | — | — | EP | claimed |
| US-6180823-B1 | CONDENSING SUBSTITUTED ACETALDEHYDE WITH ENANTIOMER OF MANDELIC ACID TO PROVIDE 5-PHENYL-1,3-DIOXOLAN-4-ONE, CONDENSING WITH CYCLOHEXANONE, DEHYDRATING PRODUCT, HYDROLYZING, REDUCING TO ALPHA-CYCLOHEXYLPHENYLGLYCOLIC ACID | SEPRACOR INC. | 2001-01-30 | — | — | US | claimed |
| WO-2000027786-A1 | STEREOSELECTIVE PROCESS FOR PREPARING (CYCLO)ALKYL PHENYLGLYCOLIC ACIDS | SEPRACOR INC. (US) | 2000-05-18 | — | — | WO | claimed |
| CN-116217909-A | Polymerization method of 1, 3-dioxolan-4-one compounds | 华东理工大学 | 2023-06-06 | — | — | CN | disclosed |
| EP-3494106-B1 | PROCESSES FOR MAKING, AND METHODS OF USING, GLYCOPYRRONIUM COMPOUNDS | JOURNEY MEDICAL CORP (US) | 2022-07-20 | — | — | EP | disclosed |
| US-11352323-B2 | Processes for making, and methods of using, glycopyrronium compounds | JOURNEY MEDICAL CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
| US-6376684-B1 | CHEMICAL INTERMEDIATE FOR OXYBUTYNIN-TYPE COMPOUNDS | SEPRACOR INC. | 2002-04-23 | — | — | US | disclosed |
| US-6376684-B1 | CHEMICAL INTERMEDIATE FOR OXYBUTYNIN-TYPE COMPOUNDS | SEPRACOR INC. | 2002-04-23 | — | — | US | disclosed |
| EP-1191930-A2 | METHODS FOR TREATMENT OF ASTHMA USING S-OXYBUTYNIN | Sepracor Inc. (US) | 2002-04-03 | — | — | EP | disclosed |
| US-6294582-B1 | THERAPY OF REVERSIBLE OBSTRUCTIVE PULMONARY DISEASE BY ADMINISTERING OPTICALLY PURE S-OXYBUTYNIN OR ITS SALT | SEPRACOR INC. | 2001-09-25 | — | — | US | disclosed |
| EP-1127043-A1 | STEREOSELECTIVE PROCESS FOR PREPARING (CYCLO)ALKYL PHENYLGLYCOLIC ACIDS | Sepracor Inc. (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-1127043-A1 | STEREOSELECTIVE PROCESS FOR PREPARING (CYCLO)ALKYL PHENYLGLYCOLIC ACIDS | Sepracor Inc. (US) | 2001-08-29 | — | — | EP | disclosed |
| US-6180823-B1 | CONDENSING SUBSTITUTED ACETALDEHYDE WITH ENANTIOMER OF MANDELIC ACID TO PROVIDE 5-PHENYL-1,3-DIOXOLAN-4-ONE, CONDENSING WITH CYCLOHEXANONE, DEHYDRATING PRODUCT, HYDROLYZING, REDUCING TO ALPHA-CYCLOHEXYLPHENYLGLYCOLIC ACID | SEPRACOR INC. | 2001-01-30 | — | — | US | disclosed |
| US-6180823-B1 | CONDENSING SUBSTITUTED ACETALDEHYDE WITH ENANTIOMER OF MANDELIC ACID TO PROVIDE 5-PHENYL-1,3-DIOXOLAN-4-ONE, CONDENSING WITH CYCLOHEXANONE, DEHYDRATING PRODUCT, HYDROLYZING, REDUCING TO ALPHA-CYCLOHEXYLPHENYLGLYCOLIC ACID | SEPRACOR INC. | 2001-01-30 | — | — | US | disclosed |
| WO-2000076490-A2 | METHODS AND COMPOSITIONS FOR TREATING URINARY FREQUENCY AND URGENCY USING OPTICALLY PURE (S)-OXYBUTYNIN | SEPRACOR INC. (US) | 2000-12-21 | — | — | WO | disclosed |
| WO-2000071108-A2 | METHODS FOR TREATMENT OF ASTHMA USING S-OXYBUTYNIN | SEPRACOR INC. (US) | 2000-11-30 | — | — | WO | disclosed |
| WO-2000027786-A1 | STEREOSELECTIVE PROCESS FOR PREPARING (CYCLO)ALKYL PHENYLGLYCOLIC ACIDS | SEPRACOR INC. (US) | 2000-05-18 | — | — | WO | disclosed |
| WO-2000027786-A1 | STEREOSELECTIVE PROCESS FOR PREPARING (CYCLO)ALKYL PHENYLGLYCOLIC ACIDS | SEPRACOR INC. (US) | 2000-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352323-B2 | Processes for making, and methods of using, glycopyrronium compounds | GYPA, TPO, CYP21A2 | TSHR 68/4885ALDH1A1 2560/4885CA2 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.