Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.40 |
| ▸ | CA2 | P00918 | 8/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | MMP13 | P45452 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531543 | 1.00 | CA1 (0.40) | CA1CA2MMP2MMP13MMP9 | |
| SCHEMBL810645 | 0.79 | ALDH1A1 (0.35) | CA1CA2MMP2MMP13MMP9 | |
| SCHEMBL810153 | 0.74 | CA1 (0.45) | CA1CA2MMP2MMP13MMP9 | |
| SCHEMBL810500 | 0.74 | ALDH1A1 (0.38) | GAAHTTALDH1A1 | |
| SCHEMBL12054705 | 0.74 | SMN1; SMN2 (0.52) | CA1CA2CA12CA9NPSR1 | |
| SCHEMBL5430213 | 0.72 | SMN1; SMN2 (0.50) | CA1CA2MMP2MMP13MMP9 | |
| SCHEMBL5430216 | 0.72 | SMN1; SMN2 (0.50) | CA1CA2MMP2MMP13MMP9 | |
| SCHEMBL4175371 | 0.71 | CA1 (0.48) | CA1CA2MMP2MMP13MMP9 | |
| SCHEMBL5796406 | 0.71 | ALDH1A1 (0.65) | MMP2MMP13MMP9MMP1MMP3 | |
| SCHEMBL14455217 | 0.71 | ALDH1A1 (0.65) | MMP2MMP13MMP9MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185488-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2002-03-13 | — | — | EP | claimed |
| WO-2000076942-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2000-12-21 | — | — | WO | claimed |
| EP-1185488-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000076942-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2000-12-21 | — | — | WO | disclosed |