Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.33 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810153 | 0.81 | CA1 (0.45) | ALDH1A1NPSR1MMP2MMP9CA1 | |
| Hexamethylbenzene SCHEMBL5418276 | 0.81 | LMNA (0.35) | ALDH1A1MMP2MMP9CA12CA1 | |
| Hexamethylbenzene SCHEMBL5418228 | 0.81 | LMNA (0.35) | ALDH1A1MMP2MMP9CA12CA1 | |
| SCHEMBL7559452 | 0.79 | CA1 (0.40) | ALDH1A1NPSR1MMP2MMP9CA12 | |
| SCHEMBL6531543 | 0.79 | CA1 (0.40) | ALDH1A1NPSR1MMP2MMP9CA12 | |
| Hexamethylbenzene SCHEMBL5423380 | 0.79 | ALDH1A1 (0.57) | ALDH1A1NPSR1SMN1; SMN2CRHBPCRHR2 | |
| Hexamethylbenzene SCHEMBL5424696 | 0.79 | ALDH1A1 (0.57) | ALDH1A1NPSR1SMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL810967 | 0.76 | ALDH1A1 (0.50) | ALDH1A1NPSR1SMN1; SMN2USP2LMNA | |
| SCHEMBL419813 | 0.76 | ALDH1A1 (0.62) | ALDH1A1NPSR1SMN1; SMN2USP2LMNA | |
| SCHEMBL810319 | 0.76 | ALDH1A1 (0.62) | ALDH1A1NPSR1SMN1; SMN2USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399895-B1 | Process for producing optically active aliphatic fluoroalcohol | KANTO KAGAKU (JP) | 2018-08-08 | — | — | EP | disclosed |
| US-9162934-B2 | Process for producing optically active alcohol | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2015-10-20 | — | — | US | disclosed |
| EP-2394977-B1 | Process for producing optically active alcohol | KANTO KAGAKU (JP) | 2014-01-08 | — | — | EP | disclosed |
| US-8558033-B2 | Process for producing optically active aliphatic fluoroalcohol | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2013-10-15 | — | — | US | disclosed |
| US-20110319671-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALIPHATIC FLUOROALCOHOL | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2011-12-29 | — | — | US | disclosed |
| EP-2399895-A2 | Process for producing optically active aliphatic fluoroalcohol | Kanto Kagaku Kabushiki Kaisha (JP) | 2011-12-28 | — | — | EP | disclosed |
| EP-2394977-A1 | Process for producing optically active alcohol | Kanto Kagaku Kabushiki Kaisha (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110282077-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110282077-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | ADH1A, ADH1C, ADH5 | ALDH1A1 32/4885NPSR1 2540/4885MMP2 2404/4885 |
| US-20110319671-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALIPHATIC FLUOROALCOHOL | ADH1A, ADH1C, ADH5 | ALDH1A1 5/4885NPSR1 2261/4885MMP2 3121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.