SCHEMBL810500

SCHEMBL810500

NC1CCCCC1NS(=O)(=O)c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.38
LMNA P02545 4/20 0.38
GAA P10253 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.36
CRHBP P24387 2/20 0.36
CRHR2 Q13324 2/20 0.36
MCOLN3 Q8TDD5 1/20 0.36
KDM4E B2RXH2 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
CNR1 P21554 3/20 0.35
THRB P10828 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL810008 0.77 MAPK1 (0.59) ALDH1A1LMNAGAASMN1; SMN2MAPK1
SCHEMBL810835 0.77 ALDH1A1 (0.53) ALDH1A1LMNAGAASMN1; SMN2TP53
SCHEMBL810153 0.76 CA1 (0.45) ALDH1A1LMNASMN1; SMN2TP53
SCHEMBL810572 0.75 ALDH1A1 (0.50) ALDH1A1LMNAGAASMN1; SMN2TP53
SCHEMBL810645 0.74 ALDH1A1 (0.35) ALDH1A1LMNASMN1; SMN2CRHBPCRHR2
SCHEMBL6531543 0.74 CA1 (0.40) ALDH1A1GAAHTT
SCHEMBL7559452 0.74 CA1 (0.40) ALDH1A1GAAHTT
SCHEMBL809747 0.74 ALDH1A1 (0.52) ALDH1A1LMNAGAASMN1; SMN2L3MBTL1
SCHEMBL810765 0.71 FABP4 (0.43) ALDH1A1GAATDP1
SCHEMBL810967 0.71 ALDH1A1 (0.50) ALDH1A1LMNASMN1; SMN2TP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2399895-B1 Process for producing optically active aliphatic fluoroalcohol KANTO KAGAKU (JP) 2018-08-08 EP disclosed
US-8558033-B2 Process for producing optically active aliphatic fluoroalcohol KANTO KAGAKU KABUSHIKI KAISHA (JP) 2013-10-15 US disclosed
US-20110319671-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALIPHATIC FLUOROALCOHOL KANTO KAGAKU KABUSHIKI KAISHA (JP) 2011-12-29 US disclosed
EP-2399895-A2 Process for producing optically active aliphatic fluoroalcohol Kanto Kagaku Kabushiki Kaisha (JP) 2011-12-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319671-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALIPHATIC FLUOROALCOHOL ADH1A, ADH1C, ADH5 ALDH1A1 5/4885LMNA 3133/4885GAA 531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.