Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA6 | P23280 | 4/20 | 0.59 |
| ▸ | CA7 | P43166 | 4/20 | 0.59 |
| ▸ | CA9 | Q16790 | 4/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA4 | P22748 | 3/20 | 0.59 |
| ▸ | CA5A | P35218 | 3/20 | 0.59 |
| ▸ | F13A1 | P00488 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | THPO | P40225 | 2/20 | 0.59 |
| ▸ | CASP2 | P42575 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CA3 | P07451 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4968222 | 0.98 | CA12 (0.55) | CA12CA6CA7CA9CA14 | |
| SCHEMBL25422005 | 0.98 | CA12 (0.62) | CA12CA6CA7CA9CA14 | |
| SCHEMBL4970774 | 0.98 | CA12 (0.55) | CA12CA6CA7CA9CA14 | |
| SCHEMBL11250246 | 0.93 | CASP2 (0.62) | CA12CA6CA7CA9CA14 | |
| SCHEMBL3432832 | 0.93 | — | — | |
| SCHEMBL246857 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL10494676 | 0.91 | — | — | |
| SCHEMBL11263323 | 0.91 | CA12 (0.60) | CA12CA6CA7CA9CA14 | |
| SCHEMBL1937058 | 0.91 | — | — | |
| SCHEMBL9243944 | 0.88 | PAOX (0.57) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107090456-A | The connection albumen led using the mediated rnai of short interfering nucleic acid（Cadherin related protein matter）, the suppression of the gene expressions of β 1 | 瑟纳治疗公司 | 2017-08-25 | — | — | CN | disclosed |
| CN-103068980-B | RNA interference mediated inhibition of the catenin (cadherin-associated protein), beta 1 (CTNNB 1) gene expression using short interfering nucleic acids (siNA) | 瑟纳治疗公司 | 2017-04-05 | — | — | CN | disclosed |
| CN-103068980-A | RNA interference mediated inhibition of the catenin (cadherin-associated protein), beta 1(CTNNB1) gene expression using short interfering nucleic acids (siNA) | MERCK SHARP & DOHME | 2013-04-24 | — | — | CN | disclosed |
| CN-101355970-A | Peptide-DICER substrate RNA conjugates as delivery vehicles for SIRNA | NASTECH PHARM CO (US) | 2009-01-28 | — | — | CN | disclosed |
| CN-101095647-A | Skin treatment article | JOHNSON & JOHNSON CONSUMER (US) | 2008-01-02 | — | — | CN | disclosed |
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | BERGERON RAYMOND J (US) | 2002-04-18 | — | — | US | disclosed |
| US-6235794-B1 | ANTICANCER AGENT | UNIVERSITY OF FLORIDA | 2001-05-22 | — | — | US | disclosed |
| WO-1998040499-A1 | GENE DELIVERY TO MUCOSAL EPITHELIUM FOR IMMUNIZATION OR THERAPEUTIC PURPOSES | DAVIS HEATHER LYNN (CA) | 1998-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | SRM, SLC7A1, CATSPER1 | CA12 3973/4885CA6 3417/4885CA7 3346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.