Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442278 | 0.89 | APOBEC3G (0.73) | APOBEC3GSLC6A4SLC6A2LMNAALDH1A1 | |
| Bipenamol SCHEMBL636892 | 0.82 | APOBEC3G (0.57) | APOBEC3GSLC6A4SLC6A2LMNAALDH1A1 | |
| Bipenamol SCHEMBL30791275 | 0.82 | APOBEC3G (0.57) | APOBEC3GSLC6A4SLC6A2LMNAALDH1A1 | |
| SCHEMBL4448364 | 0.79 | APOBEC3G (0.59) | APOBEC3GSLC6A4SLC6A2LMNAALDH1A1 | |
| SCHEMBL73812 | 0.79 | APOBEC3G (0.59) | APOBEC3GSLC6A4SLC6A2LMNAALDH1A1 | |
| Bipenamol SCHEMBL91233 | 0.79 | APOBEC3G (0.59) | APOBEC3GSLC6A4SLC6A2LDHASLC6A3 | |
| Bipenamol SCHEMBL29444593 | 0.79 | APOBEC3G (0.59) | APOBEC3GSLC6A4SLC6A2LDHASLC6A3 | |
| SCHEMBL13579946 | 0.78 | APOBEC3G (0.57) | APOBEC3GSLC6A4SLC6A2LMNAALDH1A1 | |
| SCHEMBL4677501 | 0.78 | APOBEC3G (0.57) | APOBEC3GSLC6A4SLC6A2LMNAALDH1A1 | |
| SCHEMBL8531557 | 0.78 | SLC6A4 (0.61) | APOBEC3GSLC6A4SLC6A2SLC6A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020058788-A1 | Facile deprotection of Fmoc protected amino groups | DISCOVERY PARTNERS INTERNATIONAL, INC. | 2002-05-16 | — | — | US | claimed |
| US-20020103381-A1 | Method for the synthesis of pyrazolines | CHEMRX ADVANCED TECHNOLOGIES, INC. | 2002-08-01 | — | — | US | disclosed |
| US-20020058788-A1 | Facile deprotection of Fmoc protected amino groups | DISCOVERY PARTNERS INTERNATIONAL, INC. | 2002-05-16 | — | — | US | disclosed |
| WO-2001040193-A1 | METHOD FOR THE SYNTHESIS OF PYRAZOLINES | CHEMRX ADVANCED TECHNOLOGIES, INC. (US) | 2001-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103381-A1 | Method for the synthesis of pyrazolines | CYP2F1, CYP2E1, CYP3A7 | APOBEC3G 3248/4885SLC6A4 2474/4885SLC6A2 3462/4885 |
| US-20020058788-A1 | Facile deprotection of Fmoc protected amino groups | DNPEP, LNPEP, NPEPPS | APOBEC3G 387/4885SLC6A4 2007/4885SLC6A2 2283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.