Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 18/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529843 | 0.83 | LOXL2 (0.41) | LOXL2LOX | |
| SCHEMBL27863764 | 0.78 | LOXL2 (0.66) | LOXL2LOX | |
| SCHEMBL21963284 | 0.77 | LOXL2 (0.51) | LOXL2LOX | |
| SCHEMBL1939405 | 0.74 | CA2 (0.35) | LOXL2 | |
| SCHEMBL9095386 | 0.74 | LOXL2 (0.44) | LOXL2LOX | |
| SCHEMBL9260481 | 0.73 | LOXL2 (0.37) | LOXL2LOX | |
| SCHEMBL4000697 | 0.73 | F2 (0.44) | F2 | |
| SCHEMBL6079677 | 0.72 | LOXL2 (0.49) | LOXL2LOX | |
| SCHEMBL30603083 | 0.72 | CCNE1 (0.43) | LOXL2F2 | |
| SCHEMBL9095729 | 0.72 | LOXL2 (0.40) | LOXL2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020119995-A1 | Inverse thiazolylamide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-29 | — | — | US | claimed |
| US-20020119995-A1 | Inverse thiazolylamide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119995-A1 | Inverse thiazolylamide derivatives | MAVS, DPP4, EIF2AK2 | LOXL2 4484/4885F2 4771/4885LOX 4076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.